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HHIPL2 positively governs Hedgehog signaling to accelerate non-small cell lung cancer progression via enhancing HNRNPC-mediated HNF1A mRNA stabilization.

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第一作者: Ning,Mu
第一单位: Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.;Key Laboratory of Precision Diagnosis and Treatment of Lung Tumors in Shandong Provincial Medicine and Health, Shandong University, Jinan, China.;Key Laboratory of Basic Research and Clinical Transformation of Thoracic Tumors in Shandong Provincial Colleges and Universities, Shandong University, Jinan, China.
作者: Ning,Mu [1] ; Fanrong,Liu [2] ; Xiangqing,Song [2] ; Biao,Wang [2] ; Yilin,Zhu [2] ; Lingbing,Li [2] ; Lingxiao,Yang [2] ; Huacong,Sui [2] ; Jinfu,Wang [2] ; Fengyuan,Gao [2] ; Yongjia,Zhou [2] ; Yanfeng,Lv [3] ; Zhongxian,Tian [1] ; Peichao,Li [4] ; Xiaogang,Zhao [5]
作者单位: Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.;Key Laboratory of Precision Diagnosis and Treatment of Lung Tumors in Shandong Provincial Medicine and Health, Shandong University, Jinan, China.;Key Laboratory of Basic Research and Clinical Transformation of Thoracic Tumors in Shandong Provincial Colleges and Universities, Shandong University, Jinan, China. [1] Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. [2] Department of Colorectal and Anal Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. [3] Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. lipeichao@email.sdu.edu.cn.;Key Laboratory of Precision Diagnosis and Treatment of Lung Tumors in Shandong Provincial Medicine and Health, Shandong University, Jinan, China. lipeichao@email.sdu.edu.cn.;Key Laboratory of Basic Research and Clinical Transformation of Thoracic Tumors in Shandong Provincial Colleges and Universities, Shandong University, Jinan, China. lipeichao@email.sdu.edu.cn. [4] Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. zhaoxiaogang@sdu.edu.cn.;Key Laboratory of Precision Diagnosis and Treatment of Lung Tumors in Shandong Provincial Medicine and Health, Shandong University, Jinan, China. zhaoxiaogang@sdu.edu.cn.;Key Laboratory of Basic Research and Clinical Transformation of Thoracic Tumors in Shandong Provincial Colleges and Universities, Shandong University, Jinan, China. zhaoxiaogang@sdu.edu.cn. [5]
DOI 10.1038/s41419-025-08331-3
PMID 41413056
发布时间 2025-12-18
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