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Vitamin C is essential for proper myogenic differentiation.

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第一作者： Yoshitaka,Kondo

第一单位： Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan.

作者： Yoshitaka,Kondo ^[1] ; Ayami,Sato ^[2] ; Noritsugu,Osakabe ^[3] ; Tatsuki,Minowa ^[3] ; Yung-Li,Hung ^[4] ; Shuichi,Machida ^[5] ; Akihito,Ishigami ^[6]

作者单位： Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan. ^[1] Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan; Department of Nutritional Sciences, Faculty of Health and Sports Sciences, Toyo University, Tokyo, 115-8650, Japan. Electronic address: sato190@toyo.jp. ^[2] Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan; Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, 192-0397, Japan. ^[3] Graduate School of Health and Sports Science, Juntendo University, 1-1 Hirakagakuendai, Inzai, Chiba, 270-1695, Japan. ^[4] Graduate School of Health and Sports Science, Juntendo University, 1-1 Hirakagakuendai, Inzai, Chiba, 270-1695, Japan; Institute of Health and Sports Science & Medicine, Juntendo University, 1-1 Hirakagakuendai, Inzai, Chiba, 270-1695, Japan. ^[5] Molecular Regulation of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, 173-0015, Japan; Department of Biological Sciences, Tokyo Metropolitan University, Tokyo, 192-0397, Japan. Electronic address: ishigami@tmig.or.jp. ^[6]

关键词 Ascorbic acid C2C12?cells DNA demethylation Muscle regulatory factors Myoblast Myosin heavy chain Skeletal muscle Vitamin C