Shoutai pill promotes endometrial decidualization and prevents recurrent spontaneous abortion through dual regulation of apoptosis and ECM remodeling by the LDHA-lactate axis.
第一作者:
Ruigan,Shi
第一单位:
College of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, 050091, China; Collaborative Innovation Center of Integrated Chinese and Western Medicine on Reproductive Disease, Shijiazhuang, 050091, China.
作者:
医学主题词
动物(Animals);女(雌)性(Female);细胞凋亡(Apoptosis);细胞外基质(Extracellular Matrix);妊娠(Pregnancy);流产, 习惯性(Abortion, Habitual);小鼠(Mice);蜕膜(Decidua);中草药(Drugs, Chinese Herbal);乳酸(Lactic Acid);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);L-乳酸脱氢酶(L-Lactate Dehydrogenase);疾病模型, 动物(Disease Models, Animal);糖酵解(Glycolysis);MAP激酶信号系统(MAP Kinase Signaling System);人类(Humans)
DOI
10.1016/j.jep.2025.121077
PMID
41423155
发布时间
2026-01-08
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