Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 : A Phase 2 Randomized Study.-论文-万方医学网

第一作者： Amy E,Colson

第一单位： Community Resource Initiative, Boston, and Cambridge Health Alliance, Cambridge, Massachusetts (A.E.C.).

作者： Amy E,Colson ^[1] ; Gordon E,Crofoot ^[2] ; Peter J,Ruane ^[3] ; Moti N,Ramgopal ^[4] ; Alexandra W,Dretler ^[5] ; Ronald G,Nahass ^[6] ; Gary I,Sinclair ^[7] ; Mezgebe,Berhe ^[8] ; Afsoon,Roberts ^[9] ; Shauna,Applin ^[10] ; Cynthia,Brinson ^[11] ; Dushyantha,Jayaweera ^[12] ; Kimberly A,Workowski ^[13] ; Fadi,Shihadeh ^[14] ; Shan-Yu,Liu ^[14] ; Stephanie,Klopfer ^[15] ; Cyril,Llamoso ^[15] ; Sharline,Madera ^[14] ; Hadas,Dvory-Sobol ^[14] ; Martin S,Rhee ^[14] ; Elizabeth G,Rhee ^[15] ; Jared M,Baeten ^[14] ; Joseph J,Eron ^[16]

作者单位： Community Resource Initiative, Boston, and Cambridge Health Alliance, Cambridge, Massachusetts (A.E.C.). ^[1] The Crofoot Research Center, Houston, Texas (G.E.C.). ^[2] Ruane Clinical Research, Los Angeles, California (P.J.R.). ^[3] Midway Immunology & Research Center, Fort Pierce, Florida (M.N.R.). ^[4] Metro Infectious Disease Consultants, Decatur, Georgia (A.W.D.). ^[5] IDCare, Hillsborough, New Jersey (R.G.N.). ^[6] Prism Health North Texas, Dallas, Texas (G.I.S.). ^[7] North Texas Infectious Diseases Consultants, Dallas, Texas (M.B.). ^[8] Division of Infectious Diseases, George Washington University School of Medicine and Health Sciences, Washington, DC (A.R.). ^[9] Community Health Care, Tacoma, Washington (S.A.). ^[10] Central Texas Clinical Research, Austin, Texas (C.B.). ^[11] University of Miami, Miller School of Medicine, Miami, Florida (D.J.). ^[12] Department of Medicine, Division of Infectious Diseases, Emory University, Atlanta, Georgia (K.A.W.). ^[13] Gilead Sciences, Foster City, California (F.S., S.-Y.L., S.M., H.D.-S., M.S.R., J.M.B.). ^[14] Merck & Co., Rahway, New Jersey (S.K., C.L., E.G.R.). ^[15] University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (J.J.E.). ^[16]

医学主题词人类(Humans);男(雄)性(Male);女(雌)性(Female);HIV-1(HIV-1);成年人(Adult);病毒载量(Viral Load);HIV感染(HIV Infections);中年人(Middle Aged);抗HIV药(Anti-HIV Agents);RNA, 病毒(RNA, Viral);喹诺酮类(Quinolones);腺嘌呤(Adenine);用药计划表(Drug Administration Schedule);投药, 口服(Administration, Oral);复方合剂(Drug Combinations);CD4淋巴细胞计数(CD4 Lymphocyte Count);丙氨酸(Alanine);药物疗法, 联合(Drug Therapy, Combination);杂环化合物, 3环(Heterocyclic Compounds, 3-Ring);哌嗪类(Piperazines);吲唑类(Indazoles);乙酰胺类(Acetamides);酰胺类(Amides);吡啶酮类(Pyridones)

DOI 10.7326/ANNALS-25-01939

PMID 41429026

发布时间 2026-02-16

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Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 : A Phase 2 Randomized Study.

Annals of internal medicine

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Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 : A Phase 2 Randomized Study.

Annals of internal medicine

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同项目论文

Annals of internal medicine

相关期刊

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