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Foot-and-mouth disease virus 3C protease as virulence determinant plays multiple roles in cleaving viral polyprotein and host factors.

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第一作者： Houcheng,Zhou

第一单位： College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.

作者： Houcheng,Zhou ^[1] ; Mengyao,Wang ^[1] ; Zuo,Xin ^[1] ; Zhijuan,Li ^[1] ; Qianqian,Wang ^[1] ; Yan,Li ^[2] ; Fuxiao,Liu ^[1]

作者单位： College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China. ^[1] Qingdao Center for Animal Disease Control & Prevention, Qingdao, China. ^[2]

关键词 3C protease Foot-and-mouth disease virus crystal structure innate immune response protein cleavage signaling pathway

医学主题词口蹄疫病毒(Foot-and-Mouth Disease Virus);病毒蛋白质类(Viral Proteins);多聚蛋白质类(Polyproteins);动物(Animals);毒力因子类(Virulence Factors);半胱氨酸内肽酶类(Cysteine Endopeptidases);口蹄疫(Foot-and-Mouth Disease);宿主与病原体相互作用(Host-Pathogen Interactions);毒力(Virulence)

DOI 10.1080/21505594.2025.2609570

PMID 41442432

发布时间 2026-01-04

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