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A Novel MPT-Driven Necrosis-Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids.

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第一作者： Yang,Liu

第一单位： Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment, Hangzhou, China.;Zhejiang University Cancer Center, Hangzhou, China.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.

作者： Yang,Liu ^[1] ; Liye,Tao ^[1] ; Zefeng,Shen ^[1] ; Junhao,Zheng ^[1] ; Yali,Wang ^[1] ; Meijie,Chen ^[2] ; Yangyang,Xie ^[1] ; Hongjun,Chen ^[1] ; Jingwei,Cai ^[1] ; Haoyu,Pan ^[1] ; Shihao,Li ^[1] ; Renan,Jin ^[1] ; Junjie,Xu ^[1] ; Xiao,Liang ^[3]

作者单位： Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment, Hangzhou, China.;Zhejiang University Cancer Center, Hangzhou, China.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China. ^[1] Hangzhou Medical College, Hangzhou, China. ^[2] Key Laboratory of Laparoscopic Technology of Zhejiang Province, Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.;Zhejiang Minimal Invasive Diagnosis and Treatment Technology Research Center of Severe Hepatobiliary Disease, Zhejiang Research and Development Engineering Laboratory of Minimally Invasive Technology and Equipment, Hangzhou, China.;Zhejiang University Cancer Center, Hangzhou, China.;Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.;Hangzhou Medical College, Hangzhou, China. ^[3]

关键词 HCC MPT‐driven necrosis lncRNAs organoid prognostic signature

医学主题词人类(Humans);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);预后(Prognosis);坏死(Necrosis);类器官(Organoids);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);女(雌)性(Female);男(雄)性(Male);中年人(Middle Aged);基因表达谱(Gene Expression Profiling)

DOI 10.1002/cam4.71445

PMID 41454619

发布时间 2025-12-27

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A Novel MPT-Driven Necrosis-Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids.

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A Novel MPT-Driven Necrosis-Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids.

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