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Ebola virus matrix protein VP40 triggers inflammatory responses linked to the ebolavirus virulence.

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第一作者： Satoko,Yamaoka

第一单位： Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.

作者： Satoko,Yamaoka ^[1] ; Zeineb,M'Hamdi ^[2] ; Lin,Wang ^[1] ; Vaille A,Swenson ^[3] ; Kristin L,McNally ^[4] ; Shao-Chia,Lu ^[1] ; Reema,Singh ^[2] ; Stephanie L,Saundh ^[2] ; Brady N,Zell ^[3] ; Sonja M,Best ^[5] ; Michael A,Barry ^[6] ; Angela L,Rasmussen ^[7] ; Hideki,Ebihara ^[8]

作者单位： Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905. ^[1] Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada. ^[2] Virology and Gene Therapy Track, Mayo Graduate School of Biomedical Sciences, Rochester, MN 55905. ^[3] Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840. ^[4] Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.;Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840. ^[5] Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.;Department of Immunology, Mayo Clinic, Rochester, MN 55905. ^[6] Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.;Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.;Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794. ^[7] Department of Virology 1, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo 162-8640, Japan. ^[8]

关键词 NF-κB filovirus inflammation matrix protein VP40 virulence