首页> Cancer letters> A Pt (IV)/losartan/immunotherapy Co-delivery thermosensitive gel synergizes STING activation and cancer-associated fibroblast inhibition for ovarian cancer chemoimmunotherapy.

A Pt (IV)/losartan/immunotherapy Co-delivery thermosensitive gel synergizes STING activation and cancer-associated fibroblast inhibition for ovarian cancer chemoimmunotherapy.

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第一作者： Boyuan,Liu

第一单位： School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, PR China.

作者： Boyuan,Liu ^[1] ; Zhitao,Cai ^[1] ; Haihan,Sun ^[2] ; Zixu,Liu ^[3] ; Ping,Wang ^[4] ; Ning,Dong ^[5] ; Han,Zeng ^[1] ; Chunwen,Zeng ^[1] ; Jingxin,Gou ^[1] ; Yu,Zhang ^[1] ; Tian,Yin ^[6] ; Xing,Tang ^[7] ; Haibing,He ^[8]

作者单位： School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, PR China. ^[1] School of Pharmacy, Jilin University, Changchun, 130021, Jilin, PR China. ^[2] School of Pharmacy, Yantai University, Yantai, 264005, Yantai, PR China. ^[3] School of Chemistry and Chemical Engineering, Huangshan University, Huangshan, Anhui, 245041, PR China. ^[4] Department of Pharmacy, Liaoning Jinqiu Hospital, Shenyang, 110016, Liaoning, PR China. ^[5] School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, PR China. ^[6] School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, PR China. Electronic address: tanglab@126.com. ^[7] School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, Liaoning, PR China. Electronic address: 24575816@qq.com. ^[8]

关键词 Intraperitoneal chemoimmunotherapy Peritoneal metastatic ovarian cancer Platinum prodrug TGF-β/Smad signaling pathway cGAS-STING signaling pathway