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Nasal gene expression shows a distinct signature in type 2-high asthma but not in type 2-low disease.

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第一作者: Tatiana,Karp
第一单位: Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: t.karp@umcg.nl.
作者单位: Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: t.karp@umcg.nl. [1] Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden. [2] National Heart and Lung Institute, Imperial College London, London, United Kingdom. [3] Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Respiratory Bioinformatics and Molecular Biology, University of Technology Sydney, Sydney, Australia. [4] Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. [5] Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. [6] Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. [7] Global Medical Affairs, Chiesi Farmaceutici, Parma, Italy. [8] Samuel Bronfman Department of Medicine, Icahn School of Medicine, Mount Sinai Medical Center, New York, NY. [9] Department of Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy. [10] Department of Medicine, Christian Albrechts University Kiel, Kiel, Germany; Lungen Clinic Grosshansdorf (members of the German Center for Lung Research), Grosshansdorf, Germany. [11] Section of Respiratory Medicine, Department of Translational Medicine, University of Ferrara, Ferrara, Italy. [12] Nottingham, the Institute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, United Kingdom. [13] Centre for Respiratory Medicine and Allergy, University of Manchester, Manchester University NHS Foundation Trust, Manchester, United Kingdom. [14] Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; General Practitioners Research Institute, Groningen, The Netherlands; Observational and Pragmatic Research Institute, Singapore. [15] Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. [16] Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden; Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden. [17] Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. [18]
DOI 10.1016/j.jaci.2025.10.036
PMID 41485495
发布时间 2026-04-05
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