Guaianolide sesquiterpenoids from Chrysanthemum indicum L. alleviate rheumatoid arthritis by targeting of NLRP3 inflammasome pathway.
第一作者:
Gui-Min,Xue
第一单位:
College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China; Henan Collaborative Innovation Center for Research and Development on the Whole Industry Chain of Yu-Yao, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
作者:
医学主题词
菊属(Chrysanthemum);人类(Humans);炎性体(Inflammasomes);关节炎, 类风湿(Arthritis, Rheumatoid);倍半萜类, 愈创木烷(Sesquiterpenes, Guaiane);分子结构(Molecular Structure);构效关系(Structure-Activity Relationship);白细胞介素1β(Interleukin-1beta);剂量效应关系, 药物(Dose-Response Relationship, Drug)
DOI
10.1016/j.phytochem.2026.114768
PMID
41490758
发布时间
2026-02-11
- 浏览1
Phytochemistry
114768页
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