换一批Restoration of progranulin by engineered hematopoietic stem cell-derived microglia corrects phenotypes of granulin knockout mice.
第一作者：
Yuri,Ciervo
第一单位：
Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Woman's and Child Health Department, University of Padova, Padova 35128, Italy.;Pediatric Research Institute Città della Speranza, Padova 35127, Italy.
作者：
医学主题词
动物(Animals);小神经胶质细胞(Microglia);造血干细胞(Hematopoietic Stem Cells);小鼠, 基因敲除(Mice, Knockout);表型(Phenotype);小鼠(Mice);人类(Humans);造血干细胞移植(Hematopoietic Stem Cell Transplantation);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);启动区, 遗传(Promoter Regions, Genetic)
DOI
10.1126/scitranslmed.adw9930
PMID
41499526
发布时间
2026-01-07
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Science translational medicine
eadw9930页
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