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Chemical fate in vitro: A physiological biokinetic (PBK) model for cell-based assays.

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第一作者： Daniela,Brenner

第一单位： RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic.

作者： Daniela,Brenner ^[1] ; Kévin,Bernal ^[2] ; Eliška,Sychrová ^[1] ; Jiří,Kohoutek ^[1] ; Sophie,Langouet ^[3] ; Cleo,Tebby ^[4] ; Remy,Beaudouin ^[5] ; Rayane,Boufalaas ^[6] ; Julien,Dairou ^[7] ; Arnaud,Tête ^[2] ; Pavel,Babica ^[1] ; Etienne B,Blanc ^[2] ; Iva,Sovadinová ^[1] ; Pierre-Andre,Billat ^[4]

作者单位： RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic. ^[1] Université Paris Cité, INSERM, Health & Functional Exposomics - HealthFex, Paris, France. ^[2] Université Rennes, INSERM, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France. ^[3] INERIS, Experimental toxicology and modeling unit (TEAM), Parc ALATA BP2, Verneuil en Halatte, France. ^[4] INERIS, Experimental toxicology and modeling unit (TEAM), Parc ALATA BP2, Verneuil en Halatte, France.;UMR-I 02 SEBIO, INERIS, Parc ALATA BP2, Verneuil en Halatte, France. ^[5] INERIS, Experimental toxicology and modeling unit (TEAM), Parc ALATA BP2, Verneuil en Halatte, France.;University of Technology of Compiegne, CNRS, Biomechanics and Bioengineering, Centre of recherche Royallieu, Compiegne Cedex, France. ^[6] Université Paris Cité, CNRS, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, Paris, France. ^[7]

关键词 Bayesian calibration bisphenol in vitro biokinetics new approach methodologies (NAMs)physiologically based kinetic (PBK) modeling