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A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial.

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第一作者: Clara,Fonteneau
第一单位: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA.
作者单位: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA. [1] Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA. [2] AbbVie Inc., North Chicago IL, USA. [3] Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA. [4] New York State Psychiatric Institute, New York NY, USA. [5] Vigil Neuroscience, Watertown MA, USA. [6] New York State Psychiatric Institute, New York NY, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York NY, USA; Department of Radiology, Columbia University Irving Medical Center, New York NY, USA. [7] New York State Psychiatric Institute, New York NY, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York NY, USA. [8] Investigational Drug Service, Yale New Haven Hospital, New Haven CT, USA. [9] Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA; VA Connecticut Healthcare System, West Haven CT, USA. [10] Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA; Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York NY, USA. [11] Columbia University, College of Physicians and Surgeons, New York NY, USA. [12] New York State Psychiatric Institute, New York NY, USA; Columbia University, College of Physicians and Surgeons, New York NY, USA; Nathan Kline Institute, Orangeburg NY, USA. [13] Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA; Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven CT, USA; Child Study Center, Yale University School of Medicine, New Haven CT, USA. Electronic address: youngsun.cho@yale.edu. [14]
DOI 10.1016/j.jpsychires.2025.12.020
PMID 41519104
发布时间 2026-06-09
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Journal of psychiatric research

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