Knockdown of histone H2A deubiquitinase BAP1 in human embryonic stem cells restricts their differentiation repertoire but is dispensable for maintaining their undifferentiated state.
第一作者:
Dharitree,Samal
第一单位:
Symbiosis Centre for Stem Cell Research (SCSCR), Symbiosis International (Deemed University), Pune, Maharashtra, India.
作者:
医学主题词
人类(Humans);泛素硫酯酶(Ubiquitin Thiolesterase);细胞分化(Cell Differentiation);肿瘤抑制蛋白质类(Tumor Suppressor Proteins);基因敲低技术(Gene Knockdown Techniques);组蛋白类(Histones);细胞谱系(Cell Lineage);多西环素(Doxycycline)
DOI
10.1016/j.bbrc.2026.153260
PMID
41520569
发布时间
2026-03-20
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