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Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer.

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第一作者: Valentin,Marteau
第一单位: Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.
作者单位: Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria. [1] Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland. [2] Department of Internal Medicine V, Haematology & Oncology, Comprehensive Cancer Center Innsbruck and Tyrolean Cancer Research Institute, Medical University of Innsbruck, Innsbruck, Austria. [3] Department of Visceral, Transplant and Thoracic Surgery, Medical University Innsbruck, Innsbruck, Austria. [4] Institute of General Pathology, Medical University Innsbruck, Innsbruck, Austria. [5] Department of Internal Medicine V, Haematology & Oncology, Comprehensive Cancer Center Innsbruck and Tyrolean Cancer Research Institute, Medical University of Innsbruck, Innsbruck, Austria; Tyrolpath Obrist Brunhuber GmbH, Zams, Austria. [6] Department of Therapeutic Radiology and Oncology, Medical University Innsbruck, Innsbruck, Austria. [7] Department of Molecular Life Sciences, University of Zürich, Zürich, Switzerland. [8] Department of Molecular Life Sciences, University of Zürich, Zürich, Switzerland; Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic. [9] Department of Dermatology, Venereology and Allergology, Medical University of Innsbruck, Innsbruck, Austria. [10] Senckenberg Institute of Pathology, Goethe University Frankfurt, Frankfurt, Germany; University Cancer Center Frankfurt (UCT), Frankfurt, Germany. [11] Senckenberg Institute of Pathology, Goethe University Frankfurt, Frankfurt, Germany. [12] Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum Rechts der Isar, School of Medicine & Health, Technical University of Munich, Munich, Germany. [13] Institute of Pathology, Paracelsus Medical University, Salzburg, Austria. [14] Department of Internal Medicine III, Paracelsus Medical University, Salzburg, Austria. [15] Department of Internal Medicine III, Paracelsus Medical University, Salzburg, Austria; Austrian Breast & Colorectal Cancer Study Group (ABCSG), Vienna, Austria. [16] Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands. [17] Department of Internal Medicine V, Haematology & Oncology, Comprehensive Cancer Center Innsbruck and Tyrolean Cancer Research Institute, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: dominik.wolf@i-med.ac.at. [18] Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zürich, Zürich, Switzerland. Electronic address: arnold@immunology.uzh.ch. [19] Department of Internal Medicine V, Haematology & Oncology, Comprehensive Cancer Center Innsbruck and Tyrolean Cancer Research Institute, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: stefan.salcher@i-med.ac.at. [20] Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: zlatko.trajanoski@i-med.ac.at. [21]
DOI 10.1016/j.ccell.2025.12.003
PMID 41529665
发布时间 2026-01-13
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Cancer cell

Cancer cell

2026年44卷1期

146-165.e14页

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