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Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity.

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第一作者： Danhui,Liu

第一单位： Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

作者： Danhui,Liu ^[1] ; Chuanli,Zhou ^[1] ; Xiaochen,Wang ^[1] ; Zhou,Luo ^[2] ; Ruiyao,Xu ^[1] ; Shanshan,Huo ^[1] ; Lina,Guo ^[1] ; Xuemei,Luo ^[1] ; Shuhan,Yang ^[1] ; Arielle,Click ^[1] ; Janiece,Vancil ^[1] ; Paola,Barajas ^[1] ; Victor,Mijares ^[1] ; Hamid,Baniasadi ^[3] ; Nan,Yan ^[1] ; Jan,Rehwinkel ^[4] ; Dustin C,Hancks ^[1] ; Elizabeth H,Chen ^[5] ; Shuang,Liang ^[6] ; Zhenyu,Zhong ^[6]

作者单位： Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[1] Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[2] Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[3] Medical Research Council Translational Immune Discovery Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. ^[4] Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[5] Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[6]