换一批INHBA, regulated by C/EBPβ, induces M2 macrophage polarization to promote tumor metastasis and growth via activating the PI3K/AKT pathway in gastric cancer.
第一作者：
Duan-Bo,Shi
第一单位：
Department of Pathology, Qilu Hospital, Shandong University, Jinan, China.;Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medicine, Shandong University, Jinan, Shandong, China.
作者：
医学主题词
胃肿瘤(Stomach Neoplasms);人类(Humans);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);CCAAT增强子结合蛋白β(CCAAT-Enhancer-Binding Protein-beta);动物(Animals);小鼠(Mice);巨噬细胞(Macrophages);信号传导(Signal Transduction);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);细胞增殖(Cell Proliferation);肿瘤转移(Neoplasm Metastasis);女(雌)性(Female);细胞运动(Cell Movement);男(雄)性(Male);小鼠, 裸(Mice, Nude)
DOI
10.1038/s41416-025-03326-5
PMID
41540191
发布时间
2026-03-20
- 浏览2
British journal of cancer
1031-1041页
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