首页> Tissue & cell> Astaxanthin-loaded chitosan nanoparticles attenuate chlorpyrifos-induced nephrotoxicity via activation of the Nrf2/HO-1 axis and suppression of oxidative, inflammatory, and apoptotic pathways.

Astaxanthin-loaded chitosan nanoparticles attenuate chlorpyrifos-induced nephrotoxicity via activation of the Nrf2/HO-1 axis and suppression of oxidative, inflammatory, and apoptotic pathways.

导出 LinkOut

翻译打印收藏纠错

第一作者： Ahmad A,Obaid

第一单位： Department of Physiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia. Electronic address: aaobaid@uqu.edu.sa.

作者： Ahmad A,Obaid ^[1] ; Mazen M,Ghaith ^[2] ; Ahmad Najem,Alshammari ^[3] ; Ekramy M,Elmorsy ^[4] ; Manal S,Fawzy ^[5] ; Neven A,Ebrahim ^[6] ; Hamada S,Salem ^[7] ; Nashwa Mostafa,Hussein ^[8]

作者单位： Department of Physiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia. Electronic address: aaobaid@uqu.edu.sa. ^[1] Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia. Electronic address: mmghaith@uqu.edu.sa. ^[2] Department of Medical Laboratory Technology, College of Applied Medical Sciences, Northern Border University, Arar 73213, Saudi Arabia. Electronic address: Ahmad.Alshammari2@nbu.edu.sa. ^[3] Center for Health Research Northern Border University, PO Box 1321, Arar 91431, Saudi Arabia. Electronic address: Ekramy.elmorsy@nbu.edu.sa. ^[4] Center for Health Research Northern Border University, PO Box 1321, Arar 91431, Saudi Arabia. Electronic address: Manal.Darwish@nbu.edu.sa. ^[5] Department of Basic Medical Sciences, College of Medicine, Taibah University, Madinah, Saudi Arabia; Department of Human Anatomy and Embryology, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: nevenebrahim@mans.edu.eg. ^[6] Department of Zoology, Faculty of Science, Mansoura University, Mansoura 35516, Egypt. Electronic address: hamada2012@mans.edu.eg. ^[7] Pesticide department, Faculty of agriculture Mansoura University, Mansoura 35516, Egypt. Electronic address: nashwah@mans.edu.eg. ^[8]

关键词 Apoptosis Astaxanthin nanoparticles Chlorpyrifos Inflammation Nephrotoxicity Oxidative stress