首页> Pharmaceutics> Targeted Inhibition of Oncogenic microRNAs miR-21, miR-17, and miR-155 Suppresses Tumor Growth and Modulates Immune Response in Colorectal Cancer.

Targeted Inhibition of Oncogenic microRNAs miR-21, miR-17, and miR-155 Suppresses Tumor Growth and Modulates Immune Response in Colorectal Cancer.

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第一作者： Olga,Patutina

第一单位： Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.

作者： Olga,Patutina ^[1] ; Aleksandra,Sen'kova ^[1] ; Svetlana,Miroshnichenko ^[1] ; Mona,Awad ^[2] ; Oleg,Markov ^[1] ; Daniil,Gladkikh ^[1] ; Innokenty,Savin ^[1] ; Ekaterina,Seroklinova ^[1] ; Sergey,Zhukov ^[1] ; Maxim,Kupryushkin ^[1] ; Mikhail,Maslov ^[3] ; Valentin,Vlassov ^[1] ; Marina,Zenkova ^[1]

作者单位： Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia. ^[1] Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.;Faculty of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia. ^[2] Lomonosov Institute of Fine Chemical Technologies, MIREA-Russian Technological University, 119571 Moscow, Russia. ^[3]

关键词 MDSC anti-miRs colorectal cancer immunosuppression mesyl phosphoramidate oligonucleotides miRNA thymus atrophy

DOI 10.3390/pharmaceutics18010122

PMID 41599229

发布时间 2026-01-31

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