首页> Journal of hazardous materials> PM2.5 impairs gliovascular coupling via endothelial AHR-mitochondrial signaling in mice.

PM2.5 impairs gliovascular coupling via endothelial AHR-mitochondrial signaling in mice.

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第一作者： Kyu-Sung,Kim

第一单位： Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.

作者： Kyu-Sung,Kim ^[1] ; Dong Im,Kim ^[2] ; Sungsu,Hwang ^[3] ; Inyeong,Park ^[4] ; Min-Tae,Jeon ^[4] ; Yujung,Kim ^[4] ; Suhyeon,Son ^[4] ; Jaehyeok,Lee ^[5] ; Kyemyung,Park ^[6] ; Kyuhong,Lee ^[7] ; Do-Geun,Kim ^[8]

作者单位： Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea; Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea. ^[1] Center for Respiratory Safety Research, Division of Jeonbuk Advanced Bio Research, Korea Institute of Toxicology, Jeonbuk-do 56212, Republic of Korea. ^[2] Graduate School of Health Science and Technology, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea. ^[3] Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea. ^[4] Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea. ^[5] Graduate School of Health Science and Technology, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea; Department of Biomedical Engineering, UNIST, Ulsan 44919, Republic of Korea. Electronic address: kyemyung.park@unist.ac.kr. ^[6] Center for Respiratory Safety Research, Division of Jeonbuk Advanced Bio Research, Korea Institute of Toxicology, Jeonbuk-do 56212, Republic of Korea; Department of Human and Environmental Toxicology, University of Science and Technology (UST), Daejeon 34113, Republic of Korea. Electronic address: khleekit@kitox.re.kr. ^[7] Dementia Research Group, Korea Brain Research Institute, Daegu 41062, Republic of Korea. Electronic address: kimvet0911@kbri.re.kr. ^[8]

关键词 Aquaporin-4 (AQP4)Aryl hydrocarbon receptor (AHR)Cerebral perfusion Endothelial mitochondria Glymphatic system PM2.5 Vasoconstriction