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Single-cell RNA sequencing unveils CCDC86-driven immune modulation and antigen-presenting cell dynamics in head and neck squamous cell carcinoma.

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第一作者： Xinchen,Sun

第一单位： Department of Otolaryngology and Ophthalmology, The First Clinical Medical College Nanjing University of Chinese Medicine, 210023, Nanjing, China.

作者： Xinchen,Sun ^[1] ; Bingruo,Zheng ^[1] ; Xiaoyu,Teng ^[1] ; Shanshan,Xue ^[2] ; Yongjun,Wu ^[3]

作者单位： Department of Otolaryngology and Ophthalmology, The First Clinical Medical College Nanjing University of Chinese Medicine, 210023, Nanjing, China. ^[1] Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, 210023, Nanjing, China. ^[2] Department of Otolaryngology and Ophthalmology, The First Clinical Medical College Nanjing University of Chinese Medicine, 210023, Nanjing, China. wooyongjun@126.com.;Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, 210023, Nanjing, China. wooyongjun@126.com. ^[3]

关键词 Antigen-presenting cells CCDC86 Head and neck squamous cell carcinoma Immune evasion Single-cell RNA sequencing Tumor immune microenvironment

DOI 10.1007/s12672-025-04134-2

PMID 41661401

发布时间 2026-02-13

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Single-cell RNA sequencing unveils CCDC86-driven immune modulation and antigen-presenting cell dynamics in head and neck squamous cell carcinoma.

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Single-cell RNA sequencing unveils CCDC86-driven immune modulation and antigen-presenting cell dynamics in head and neck squamous cell carcinoma.

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