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Systematic analysis of biological endpoint variability and implications for quantitative modeling of the FLASH sparing effect.

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第一作者： Isabella,Colizzi

第一单位： Center for Proton Therapy, Paul Scherrer Institut, 5232 Villigen, PSI, Switzerland.;Department of Physics, ETH Zurich 8092 Zurich, Switzerland.

作者： Isabella,Colizzi ^[1] ; Mathilde,Toschini ^[1] ; Antony J,Lomax ^[1] ; Serena,Psoroulas ^[2]

作者单位： Center for Proton Therapy, Paul Scherrer Institut, 5232 Villigen, PSI, Switzerland.;Department of Physics, ETH Zurich 8092 Zurich, Switzerland. ^[1] Center for Proton Therapy, Paul Scherrer Institut, 5232 Villigen, PSI, Switzerland.;Department of Radiation Oncology, University Hospital Zurich (USZ), University of Zurich (UZH), Raemistrasse 100, CH-8091 Zurich, Switzerland. ^[2]

关键词 Endpoints FLASH FLASH effect Guidelines Meta-analysis Modelling Preclinical studies UHDR

DOI 10.1016/j.phro.2026.100915

PMID 41696018

发布时间 2026-02-18

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Physics and imaging in radiation oncology

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Systematic analysis of biological endpoint variability and implications for quantitative modeling of the FLASH sparing effect.

Physics and imaging in radiation oncology

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Physics and imaging in radiation oncology

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Systematic analysis of biological endpoint variability and implications for quantitative modeling of the FLASH sparing effect.

Physics and imaging in radiation oncology

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Physics and imaging in radiation oncology

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