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Monocyte-derived IL-10 drives sex differences in pain duration.

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第一作者： Jaewon,Sim

第一单位： Department of Physiology, Michigan State University, East Lansing, MI, USA.;Cell and Molecular Biology Graduate program, Michigan State University, East Lansing, MI, USA.

作者： Jaewon,Sim ^[1] ; Elizabeth,O'Guin ^[2] ; Chiho,Sugimoto ^[2] ; Sophie,Laumet ^[2] ; Karli,Monahan ^[2] ; Matthew P,Bernard ^[3] ; Samuel A,McLean ^[4] ; Liz M,Albertorio-Sáez ^[5] ; Ying,Zhao ^[5] ; Hariharan,Ramakrishnan ^[2] ; Sabrina,de Souza ^[2] ; Olivia C,Eller ^[6] ; Christine J,Smoyer ^[7] ; Kyle M,Baumbauer ^[8] ; Matthias,Mack ^[9] ; Joseph K,Folger ^[2] ; Alfred J,Robison ^[10] ; Sarah D,Linnstaedt ^[5] ; Geoffroy,Laumet ^[10]

作者单位： Department of Physiology, Michigan State University, East Lansing, MI, USA.;Cell and Molecular Biology Graduate program, Michigan State University, East Lansing, MI, USA. ^[1] Department of Physiology, Michigan State University, East Lansing, MI, USA. ^[2] Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI, USA. ^[3] Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ^[4] Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ^[5] Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA. ^[6] Kansas Intellectual and Developmental Disabilities Research Center, University of Kansas Medical Center, Kansas City, KS, USA. ^[7] Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, KS, USA. ^[8] Department of Nephrology, University Hospital Regensburg, Regensburg, Germany. ^[9] Department of Physiology, Michigan State University, East Lansing, MI, USA.;Neuroscience Program, Michigan State University, East Lansing, MI, USA. ^[10]

医学主题词白细胞介素10(Interleukin-10);动物(Animals);单核细胞(Monocytes);女(雌)性(Female);男(雄)性(Male);小鼠(Mice);人类(Humans);性征(Sex Characteristics);小鼠, 近交C57BL(Mice, Inbred C57BL);疼痛(Pain);小鼠, 基因敲除(Mice, Knockout);感觉感受器细胞(Sensory Receptor Cells);成年人(Adult)

DOI 10.1126/sciimmunol.adx0292

PMID 41719383

发布时间 2026-02-20

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