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Synthesis and biological evaluation of 6-hydroxychromone based thiosemicarbazones as potential antidiabetic and antioxidant agents.

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第一作者： Wajeeha,Zareen

第一单位： Institute of Chemical Sciences, Bahauddin Zakariya University, 60800, Multan, Pakistan.

作者： Wajeeha,Zareen ^[1] ; Nadeem,Ahmed ^[2] ; Farhan,Siddique ^[3] ; Parham,Taslimi ^[4] ; Muhammad Ali,Khan ^[1] ; Talha,Islam ^[5] ; Mostafa A,Ismail ^[6] ; Mariya,Al-Rashida ^[5] ; Magdi E A,Zaki ^[7] ; Sobhi M,Gomha ^[8] ; Rima D,Alharthy ^[9] ; Zahid,Shafiq ^[10]

作者单位： Institute of Chemical Sciences, Bahauddin Zakariya University, 60800, Multan, Pakistan. ^[1] Institute of Chemical Sciences, Bahauddin Zakariya University, 60800, Multan, Pakistan.;College of Chemistry & Chemical Engineering, Central South University, Changsha, 410083, Hunan, China. ^[2] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan. ^[3] Department of Biotechnology, Faculty of Science, Bartin University, 74110, Bartin, Turkey. ^[4] Department of Chemistry, Forman Christian College (A Chartered University), Ferozepur Road 54600, Lahore, Pakistan. ^[5] Department of Chemistry, Faculty of Science, Research Center for Advanced Materials Science (RCAMS), King Khalid University, P.O. Box 960, Abha, 61421, Saudi Arabia. ^[6] Department of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia. ^[7] Department of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah, 42351, Saudi Arabia. smgomha@iu.edu.sa. ^[8] Department of Chemistry, Rabigh Branch, Science & Arts College, King Abdulaziz University, Rabigh, 21911, Saudi Arabia. ^[9] Institute of Chemical Sciences, Bahauddin Zakariya University, 60800, Multan, Pakistan. zahidshafiq@bzu.edu.pk. ^[10]

关键词 6-Hydroxychromone Antidiabetic Antioxidant Enzyme inhibition Molecular docking Thiosemicarbazones

DOI 10.1038/s41598-026-40449-y

PMID 41724772

发布时间 2026-02-24

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