Metformin is associated with the suppression of the TNF-α/iNOS/TIMP-1 axis-mediated liver injury and fibrosis secondary to diabetes.
第一作者:
Hind,Zafrah
第一单位:
Department of Physiology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
作者:
医学主题词
动物(Animals);二甲双胍(Metformin);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);金属蛋白酶1组织抑制剂(Tissue Inhibitor of Metalloproteinase-1);一氧化氮合酶Ⅱ型(Nitric Oxide Synthase Type II);肝硬化(Liver Cirrhosis);大鼠(Rats);男(雄)性(Male);肝(Liver);糖尿病, 实验性(Diabetes Mellitus, Experimental);糖尿病, 2型(Diabetes Mellitus, Type 2);降血糖药(Hypoglycemic Agents)
DOI
10.1016/j.tice.2026.103425
PMID
41764858
发布时间
2026-06-12
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Tissue & cell
103425页
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