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Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry.

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第一作者： Alexander S,Lee

第一单位： Departments of Chemistry and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, Illinois 60208, United States.;Simpson Querry Center for Epigenetics and Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, United States.

作者： Alexander S,Lee ^[1] ; Nickolas P,Fisher ^[2] ; Matthew R,Marunde ^[3] ; Pei,Su ^[2] ; Laiba F,Khan ^[3] ; Ryan J,Ezell ^[3] ; Zachary B,Gillespie ^[3] ; Bria,Graham ^[3] ; Hailey F,Taylor ^[3] ; Ugochi C,Onuoha ^[3] ; Taojunfeng,Su ^[2] ; Kevin,Jooß ^[2] ; Luis F,Schachner ^[2] ; Harrison A,Fuchs ^[4] ; Kelsey,Noll ^[3] ; Matthew J,Meiners ^[3] ; Marcus A,Cheek ^[3] ; Jonathan M,Burg ^[3] ; Zu-Wen,Sun ^[3] ; Catherine A,Musselman ^[4] ; Michael-Christopher,Keogh ^[3] ; Neil L,Kelleher ^[1]

作者单位： Departments of Chemistry and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, Illinois 60208, United States.;Simpson Querry Center for Epigenetics and Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, United States. ^[1] Departments of Chemistry and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, Illinois 60208, United States. ^[2] EpiCypher, Inc., Research Triangle Park, Durham, North Carolina 27709, United States. ^[3] Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, United States. ^[4]

DOI 10.1021/acscentsci.5c00736

PMID 41768765

发布时间 2026-03-10

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ACS central science

2026年12卷2期

208-221页

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ACS central science

2026年12卷2期

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Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry.

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