首页> Journal of medicinal chemistry> Discovery of 1-(Azetidin-3-ylmethyl)-1H-benzo[d]imidazole Derivatives as Efficient GSTP1 Inhibitors for Gastric Cancer Treatment via Warhead Removal Strategy.

Discovery of 1-(Azetidin-3-ylmethyl)-1H-benzo[d]imidazole Derivatives as Efficient GSTP1 Inhibitors for Gastric Cancer Treatment via Warhead Removal Strategy.

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第一作者： Wenhao,Xie

第一单位： School of Pharmacy, Fudan University, Shanghai 201203, China.

作者： Wenhao,Xie ^[1] ; Yuehong,Chen ^[2] ; Lulu,Jiang ^[3] ; Xinyuan,Wu ^[4] ; Zhiyuan,Qi ^[1] ; Tianbai,Shuai ^[1] ; Mingzhong,Yang ^[1] ; Zhiyang,Wang ^[1] ; Jinghan,Gao ^[5] ; Yingjie,Zhu ^[4] ; Xiaojie,Lu ^[4] ; Min,Huang ^[6] ; Zhibei,Qu ^[1] ; Wenfu,Tan ^[1] ; Jian,Ding ^[7] ; Lu,Zhou ^[1]

作者单位： School of Pharmacy, Fudan University, Shanghai 201203, China. ^[1] School of Pharmacy, Fudan University, Shanghai 201203, China.;State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 201203, China. ^[2] School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China. ^[3] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 201203, China. ^[4] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 201203, China.;Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province 210023, China. ^[5] State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 201203, China.;Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China. ^[6] School of Pharmacy, Fudan University, Shanghai 201203, China.;State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 201203, China.;Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China. ^[7]