首页> Nanomedicine (London, England)> Injectable etoposide-loaded dextran nanoparticles for ‎breast cancer treatment: physicochemical characterization, cytotoxicity ‎studies, macrophage activity, and gene expression profiling.

Injectable etoposide-loaded dextran nanoparticles for ‎breast cancer treatment: physicochemical characterization, cytotoxicity ‎studies, macrophage activity, and gene expression profiling.

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第一作者： Sivakumar S,Moni

第一单位： Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.;Health Research Centre, Jazan University, Jazan, Saudi Arabia.

作者： Sivakumar S,Moni ^[1] ; Marwa M,Qadri ^[2] ; Jobran M,Moshi ^[3] ; Yousef M,Hawsawi ^[4] ; Shmoukh,Alotaibi ^[5] ; Yassine,Riadi ^[6] ; Hatim Ali Asiri,Halawi ^[7] ; Muhammad H,Sultan ^[8] ; Ahmad,Salawi ^[8] ; Nader,Kameli ^[3] ; Ahmed Ali,Mobarki ^[9] ; Majed Ahmed,Kaabi ^[9] ; Zia Ur,Rehman ^[10] ; Mohamed Eltaib,Elmobark ^[8] ; Ieman A,Aljahdali ^[11] ; Bassem,Oraibi ^[12] ; Haneen Mohammed,Shabaj ^[2] ; Mohammed A,Jeraiby ^[13]

作者单位： Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.;Health Research Centre, Jazan University, Jazan, Saudi Arabia. ^[1] Health Research Centre, Jazan University, Jazan, Saudi Arabia.;Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, Jazan, Saudi Arabia. ^[2] Health Research Centre, Jazan University, Jazan, Saudi Arabia.;Department of Medical Laboratory Technology, College of Nursing and Health Science, Jazan University, Jazan, Saudi Arabia. ^[3] Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.;Department of Biochemistry and Molecular Medicine, College of Medicine, Al-Faisal University, Riyadh, Saudi Arabia. ^[4] Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia. ^[5] Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia. ^[6] Hematology/Oncology Center, Jazan Health Cluster, Jazan Specialist Hospital, Jazan, Saudi Arabia. ^[7] Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia. ^[8] Pharm.D Students, College of Pharmacy, Jazan University, Jazan, Saudi Arabia. ^[9] Health Research Centre, Jazan University, Jazan, Saudi Arabia.;Department of Pharmaceutical Chemistry and Pharmacognosy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia. ^[10] Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia. ^[11] Health Research Centre, Jazan University, Jazan, Saudi Arabia. ^[12] Department of Basic Medical Science, College of Medicine, Jazan University, Jazan, Saudi Arabia. ^[13]

关键词 BCL2 Bax Breast cancer apoptosis ? ?etoposide-loaded dextran sulfate nanoparticles ??(ETP-DNP)p53 ?cytotoxicity ?ionotropic gelation technique