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Integrated multi-omics analysis reveals that MARCKS reprograms the immunosuppressive microenvironment to drive hepatocellular carcinoma progression.

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第一作者： Haifei,Qin

第一单位： Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China.;Guangxi Key Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer, Nanning, PR China.;Key Laboratory of Early Prevention & Treatment for Regional High Frequency Tumor (Guangxi Medical University), Ministry of Education, Nanning, PR China.

作者： Haifei,Qin ^[1] ; Qinchen,Lu ^[1] ; Baicheng,Hu ^[1] ; Xin,Zhou ^[1] ; Chenlu,Lan ^[1] ; Honglong,Lu ^[1] ; Donghua,Gao ^[1] ; Chongjiu,Qin ^[1] ; Kai,Peng ^[1] ; Yongguang,Wei ^[1] ; Xiwen,Liao ^[1] ; Tao,Peng ^[2] ; Liming,Shang ^[3] ; Guangzhi,Zhu ^[4]

作者单位： Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China.;Guangxi Key Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer, Nanning, PR China.;Key Laboratory of Early Prevention & Treatment for Regional High Frequency Tumor (Guangxi Medical University), Ministry of Education, Nanning, PR China. ^[1] Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China. pengtaogmu@163.com.;Guangxi Key Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer, Nanning, PR China. pengtaogmu@163.com.;Key Laboratory of Early Prevention & Treatment for Regional High Frequency Tumor (Guangxi Medical University), Ministry of Education, Nanning, PR China. pengtaogmu@163.com. ^[2] Department of Hepatobiliary Surgery, Beihai People's Hospital, Beihai, PR China. 231614649@qq.com. ^[3] Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR China. zhuguangzhi0792@hotmail.com.;Guangxi Key Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer, Nanning, PR China. zhuguangzhi0792@hotmail.com.;Key Laboratory of Early Prevention & Treatment for Regional High Frequency Tumor (Guangxi Medical University), Ministry of Education, Nanning, PR China. zhuguangzhi0792@hotmail.com. ^[4]

DOI 10.1038/s41698-026-01372-7

PMID 41813922

发布时间 2026-05-16

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NPJ precision oncology

2026年10卷1期

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NPJ precision oncology

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Integrated multi-omics analysis reveals that MARCKS reprograms the immunosuppressive microenvironment to drive hepatocellular carcinoma progression.

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Integrated multi-omics analysis reveals that MARCKS reprograms the immunosuppressive microenvironment to drive hepatocellular carcinoma progression.

NPJ precision oncology

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NPJ precision oncology

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