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Intermediate dose heparin thromboprophylaxis among critically ill patients with COVID-19: a randomized clinical trial.

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第一单位: Faculty of Health Sciences, University of Bristol, Bristol, UK. Electronic address: c.bradbury@bristol.ac.uk.
作者: Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia (REMAP-CAP) Investigators [1] ; Charlotte A,Bradbury [2] ; Bryan J,McVerry [3] ; Patrick R,Lawler [2] ; Derek C,Angus [4] ; Djillali,Annane [5] ; Yaseen M,Arabi [6] ; Diptesh,Aryal [7] ; Carly,Au [8] ; Abigail,Beane [9] ; Scott M,Berry [9] ; Lindsay R,Berry [10] ; Janis,Best-Lane [11] ; Shailesh,Bihari [12] ; Marc,Bonten [13] ; Frank,Brunkhorst [14] ; Aidan,Burrell [15] ; Meredith,Buxton [16] ; Marc,Carrier [17] ; Maurizio,Cecconi [14] ; Allen C,Cheng [18] ; Matthew,Cove [12] ; Lennie P G,Derde [9] ; Michelle A,Detry [19] ; Lise J,Estcourt [16] ; Dean A,Fergusson [9] ; Mark,Fitzgerald [20] ; Rob A,Fowler [20] ; Ewan C,Goligher [14] ; Cameron,Green [21] ; Rashan,Haniffa [7] ; David A,Harrison [22] ; Leanne M C,Hays [14] ; Alisa M,Higgins [23] ; Thomas,Hills [24] ; Christopher M,Horvat [2] ; David T,Huang [25] ; Beverley J,Hunt [26] ; Nao,Ichihara [27] ; Devachandran,Jayakumar [7] ; Stephanie,Keattch [28] ; Anand,Kumar [10] ; Michael A,Laffan [29] ; Francois,Lamontagne [2] ; Christine M,Leeper [9] ; Roger J,Lewis [9] ; Elizabeth,Lorenzi [28] ; Sylvain A,Lother [30] ; John C,Marshall [31] ; Colin J,McArthur [32] ; Daniel F,McAuley [9] ; Anna,McGlothlin [14] ; Shay P,McGuinness [14] ; Zoe K,McQuilten [33] ; Saskia,Middeldorp [34] ; Susan,Morpeth [7] ; Paul R,Mouncey [35] ; Srinivas,Murthy [2] ; Matthew D,Neal [36] ; Alistair D,Nichol [31] ; Rachael L,Parke [14] ; Jane C,Parker [37] ; Svenja,Peters [38] ; Lusi Felipe,Reyes [7] ; Kathryn,Rowan [39] ; Hiroki,Saito [30] ; Marlene,Santos [9] ; Christina T,Saunders [12] ; Roger E G,Schutgens [2] ; Christopher W,Seymour [40] ; Manu Shankar,Hari [14] ; Vanessa,Singh [8] ; Simon J,Stanworth [41] ; Alexis F,Turgeon [23] ; Anne M,Turner [33] ; Frank L,van de Veerdonk [42] ; Anthony C,Gordon [14] ; Steve A,Webb [43] ; Ryan,Zarychanski
作者单位: Faculty of Health Sciences, University of Bristol, Bristol, UK. Electronic address: c.bradbury@bristol.ac.uk. [1] University of Pittsburgh, Pittsburgh, Pennsylvania, USA. [2] Peter Munk Cardiac Centre at University Health Network, Toronto, Canada; University of Toronto, Toronto, Canada. [3] Université Versailles Saint-Quentin-en-Yvelines - Université Paris Saclay, Montigny-le-Bretonneux, France. [4] King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Ara. [5] Nepal Mediciti Hospital, Lalitpur, Nepal. [6] Intensive Care National Audit & Research Centre (ICNARC), London, UK. [7] Oxford University, Oxford, UK. [8] Berry Consultants, Austin, Texas, USA. [9] Imperial College London, London, UK. [10] Flinders University, Bedford Park, Australia. [11] University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. [12] Jena University Hospital, Jena, Germany. [13] Monash University, Melbourne, Australia. [14] Global Coalition for Adaptive Research, Los Angeles, California, USA. [15] Ottawa Hospital Research Institute, Ottawa, Canada. [16] Humanitas Research Hospital, Rozzano (Milan), Italy. [17] Yong Loo Lin School of Medicine, National University of Singapore, Singapore. [18] National Health Service Blood and Transplant, Oxford, UK. [19] University of Toronto, Toronto, Canada. [20] University of Oxford, Bangkok, Thailand. [21] University College Dublin Clinical Research Centre, St Vincent's University Hospital, Dublin, Ireland. [22] Medical Research Institute of New Zealand (MRINZ), Wellington, New Zealand. [23] University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, Pennsylvania, USA. [24] Kings Healthcare Partners, London, UK. [25] The University of Tokyo, Tokyo, Japan. [26] Apollo Speciality Hospital - Old Mahabalipuram Road, Chennai, India. [27] University of Manitoba, Winnipeg, Canada. [28] Université de Sherbrooke, Sherbrooke, Canada. [29] St. Michael's Hospital Unity Health, Toronto, Canada. [30] Auckland City Hospital, Auckland, New Zealand. [31] Queen's University Belfast, Belfast, Northern Ireland, UK. [32] Radboud University Medical Center, Nijmegen, the Netherlands. [33] Middlemore Hospital, Auckland, New Zealand. [34] University of British Columbia, Vancouver, Canada. [35] University College Dublin, Clinical Research Centre at St Vincent's University Hospital, Dublin, Ireland. [36] European Clinical Research Alliance on Infectious Diseases (ECRAID), Utrecht, the Netherlands. [37] Universidad de La Sabana, Chia, Colombia. [38] St Marianna University School of Medicine, Yokohama City Seibu Hospital, Yokohama, Japan. [39] King's College London, London, UK. [40] Université Laval, Québec City, Canada. [41] Imperial College London, London, UK; Imperial College Healthcare National Health Service Trust, St. Mary's Hospital, London, UK. [42] University of Manitoba, Winnipeg, Canada; CancerCare Manitoba, Winnipeg, Canada. [43]
DOI 10.1016/j.jtha.2026.03.006
PMID 41895526
发布时间 2026-04-12
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Journal of thrombosis and haemostasis : JTH

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