Hsa-miR-99a deficiency contributes to MSI-H colorectal cancer progression by activating the mTOR pathway and inducing Th1/Th2 imbalance.
第一作者:
Xuejing,Yang
第一单位:
Department of Thoracic Oncology, Cancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
作者:
医学主题词
人类(Humans);微RNAs(MicroRNAs);结直肠肿瘤(Colorectal Neoplasms);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);微卫星不稳定性(Microsatellite Instability);信号传导(Signal Transduction);Th2细胞(Th2 Cells);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);Th1细胞(Th1 Cells);疾病恶化(Disease Progression);肿瘤微环境(Tumor Microenvironment);女(雌)性(Female);男(雄)性(Male);中年人(Middle Aged)
DOI
10.3389/fimmu.2026.1796084
PMID
41924263
发布时间
2026-04-02
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Frontiers in immunology
1796084页
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