Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.
第一作者:
Mary,Feitosa
第一单位:
Washington School of Medicine.
作者:
Mary,Feitosa [1]
;
Karen,Schwander [2]
;
Clint,Miller [3]
;
Aldi,Kraja [4]
;
Amy,Bentley [5]
;
Michael,Brown [6]
;
Hannah,de Hesselle [7]
;
Raymond,Noordam [8]
;
Songmi,Lee [9]
;
Pavithra,Nagarajan [10]
;
Heming,Wang [11]
;
Ayush,Giri [12]
;
Farrah,Ammous [13]
;
Traci,Bartz [14]
;
Chiara,Batini [15]
;
Jean-Tristan,Brandenburg [16]
;
Max,Breyer [17]
;
Heather,Cordell [18]
;
Janie,Corley [19]
;
Latchezar,Dimotrov [20]
;
Anh,Do [10]
;
Jiawen,Du [21]
;
Franco,Giulianini [22]
;
Christopher,Grace [23]
;
Valborg,Gudmundsdottir [6]
;
Xiuqing,Guo [7]
;
Sarah,Harris [24]
;
Natalie,Hasbani [25]
;
Janina,Herold [10]
;
Keiko,Hikino [26]
;
Edith,Hofer [27]
;
Andrea,Horimoto [28]
;
Fang-Chi,Hsu [29]
;
Zhijie,Huang [30]
;
Anne,Jackson [31]
;
Chang Hoon,Kang [32]
;
Federica,Laguzzi [33]
;
Timo,Lakka [34]
;
Christophe,Lefevre [35]
;
Jian'an,Luan [36]
;
Leo-Pekka,Lyytikäinen [37]
;
Aline,Meirhaeghe [38]
;
Manon,Muntaner [39]
;
Masahiro,Nakatochi [40]
;
Giuseppe Giovanni,Nardone [41]
;
Ilja,Nolte [42]
;
Teresa,Nutile [43]
;
Nicholette,Palmer [44]
;
Amit,Patki [45]
;
Alessandro,Pecori [46]
;
Varun,Rao [47]
;
Anne,Richmond [48]
;
Mercedes,Richter [13]
;
Mihir,Sanghvi [49]
;
Aurora,Santin [50]
;
Heather,Stringham [51]
;
Fumihiko,Takeuchi [52]
;
Ye An,Tan [53]
;
Jingxian,Tang [8]
;
Maris,Teder-Laving [54]
;
Olga,Trofimova [55]
;
Stella,Trompet [42]
;
Peter,van der Most [8]
;
Ya Xing,Wang [13]
;
Zhe,Wang [56]
;
Yujie,Wang [57]
;
Wenyi,Wang [58]
;
Erin,Ware [12]
;
Stefan,Weiss [4]
;
Kenneth,Westerman [4]
;
Chenglong,Yu [39]
;
Wanying,Zhu [59]
;
Md Abu Yusuf,Ansari [60]
;
Pramod,Anugu [14]
;
Anna,Argoty-Pantoja [61]
;
John,Attia [14]
;
Bernhard,Banas [62]
;
Lydia,Bazzano [18]
;
Joshua,Bis [63]
;
Carsten,Boger [64]
;
Jennifer,Brody [65]
;
Ulrich,Broeckel [66]
;
Harry,Campbell [67]
;
Archie,Campbell [15]
;
Pasqualina,Cennamo [13]
;
William,Checkley [68]
;
Miao-Li,Chee [69]
;
Guanjie,Chen [12]
;
Yii-Der,Chen [70]
;
Kayesha,Coley [25]
;
Stacey,Collins [13]
;
Jean,Dallongeville [71]
;
Hithanadura Janaka,de Silva [72]
;
Charles,Dupont [21]
;
Todd,Edwards [7]
;
Christian,Enzinger [73]
;
Jessica,Faul [74]
;
Lilian Fernandes,Silva [75]
;
Adam,Gepner [76]
;
Anuj,Goel [13]
;
Mathias,Gorski [77]
;
Mariaelisa,Graff [78]
;
C Charles,Gu [79]
;
Jiang,He [80]
;
Sami,Heikkinen [13]
;
Erin,Hill-Burns [29]
;
Adriana,Hung [81]
;
Steven,Hunt [82]
;
Marguerite,Irvin [83]
;
Mika,Kähönen [84]
;
Sharon,Kardia [85]
;
Minjung,Kho [86]
;
Heikki,Koistinen [87]
;
Ivana,Kolčić [88]
;
Pirjo,Komulainen [58]
;
José Eduardo,Krieger [89]
;
Lenore,Launer [90]
;
Daniel,Levy [91]
;
Jianjun,Liu [71]
;
Joseph,McCormick [92]
;
John,McNeil [93]
;
Yuri,Milaneschi [94]
;
Jaime,Miranda [95]
;
Kari,North [96]
;
Anniina,Oravilahti [74]
;
Alison,Pattie [97]
;
Patricia,Peyser [8]
;
Giulia,Pianigiani [40]
;
Leslie,Raffel [18]
;
Olli,Raitakari [98]
;
Michele,Ramsay [16]
;
Salil,Redkar [99]
;
Paul,Redmond [13]
;
Paul,Ridker [100]
;
Frits,Rosendaal [18]
;
Daniela,Ruggiero [101]
;
Tom,Russ [102]
;
Charumathi,Sabanayagam [98]
;
Alyssa,Scartozzi [103]
;
Reinhold,Schmidt [104]
;
Laura,Scott [105]
;
Rodney,Scott [15]
;
Susan,Shenkin [106]
;
Roelof,Smit [48]
;
Jennifer A,Smith [107]
;
Zhi,Da Soh [12]
;
Beatrice,Spedicati [108]
;
David,Stott [109]
;
Quan,Sun [110]
;
Gerald,Sze [111]
;
E Shyong,Tai [112]
;
Paola,Tesolin [113]
;
Rima,Triatin [69]
;
Nataraja Sarma,Vaitinadin [8]
;
Rob,van Dam [98]
;
Julien,Vaucher [114]
;
Uwe,Völker [115]
;
Henry,Völzke [114]
;
Chaolong,Wang [7]
;
Helen,Warren [116]
;
Rajitha,Wickremasinghe [117]
;
Ko,Willems van Dijk [53]
;
Cancan,Xue [118]
;
Ken,Yamamoto [13]
;
Jie,Yao [119]
;
Mitsuhiro,Yokota [26]
;
Martina,Zimmermann [10]
;
Philippe,Amouyel [120]
;
Jennifer,Below [121]
;
Sven,Bergmann [122]
;
Antonio,Bernabe-Ortiz [123]
;
Michael,Boehnke [68]
;
Palwende,Boua [18]
;
LifeLines Cohort study [124]
;
Donald,Bowden [4]
;
Daniel,Chasman [125]
;
Ching-Yu,Cheng [19]
;
Marina,Ciullo [126]
;
Maria Pina,Concas [93]
;
Simon R,Cox [127]
;
Luc,Dauchet [128]
;
Ian,Deary [129]
;
Stephan,Felix [130]
;
Ervin,Fox [15]
;
Nora,Franceschini [131]
;
Barry,Freedman [8]
;
Paolo,Gasparini [52]
;
Giorgia,Girotto [132]
;
Vilmundur,Gudnason [133]
;
Caroline,Hayward [134]
;
Iris,Heid [71]
;
Elizabeth,Holliday [58]
;
Sahoko,Ichihara [135]
;
Catherine,John [30]
;
Jost,Jonas [29]
;
J Wouter,Jukema [136]
;
Mart,Kals [137]
;
Norihiro,Kato [138]
;
Bernard,Keavney [101]
;
Tanika,Kelly [139]
;
Markku,Laakso [140]
;
Paul,Lacaze [141]
;
Leslie,Lange [142]
;
Karin,Leander [143]
;
Seunggeun,Lee [144]
;
Terho,Lehtimäki [145]
;
Changwei,Li [146]
;
Ching-Ti,Liu [147]
;
Ruth,Loos [120]
;
Brenda,Penninx [54]
;
Alexandre,Pereira [148]
;
Ozren,Polasek [149]
;
Bruce,Psaty [26]
;
Rainer,Rauramaa [33]
;
Charles,Rotimi [150]
;
Jerome,Rotter [13]
;
Igor,Rudan [73]
;
Helena,Schmidt [13]
;
Xueling,Sim [151]
;
Harold,Snieder [6]
;
Klaus,Stark [6]
;
Chikashi,Terao [152]
;
Lynne,Wagenknecht [153]
;
Nicholas,Wareham [154]
;
Hugh,Watkins [6]
;
David,Weir [74]
;
Kristin,Young [155]
;
Wei,Zhao [156]
;
William,Gauderman [2]
;
Alanna,Morrison [148]
;
Myriam,Fornage ;
Han,Chen ;
Jeffrey,O'Connell ;
Alisa,Manning ;
Paul,de Vries ;
Lisa,de Las Fuentes ;
Dabeeru,Rao ;
Patricia,Munroe ;
Michael,Province ;
Thomas,Winkler
作者单位:
Washington School of Medicine.
[1]
Washington University.
[2]
University of Virginia.
[3]
University of Mississippi Medical Center.
[4]
National Institutes of Health, NHGRI.
[5]
The University of Texas Health Science Center at Houston.
[6]
University of Regensburg.
[7]
Leiden University Medical Center.
[8]
University of Texas Health Science Center at Houston, McGovern Medical School.
[9]
Brigham and Women's Hospital.
[10]
Brigham and Women's Hospital; Harvard Medical School.
[11]
Vanderbilt University Medical Center.
[12]
University of Michigan.
[13]
University of Washington.
[14]
University of Leicester.
[15]
Vanderbilt University School of Medicine.
[16]
Newcastle University.
[17]
University of Edinburgh.
[18]
Wake Forest University School of Medicine.
[19]
Washington University School of Medicine, St. Louis, MO, USA.
[20]
Radcliffe Department of Medicine, University of Oxford.
[21]
Faculty of Medicine, University of Iceland.
[22]
Lothian Birth Cohorts, Dept. Psychology.
[23]
RIKEN.
[24]
Medical University Graz.
[25]
Wake Forest School of Medicine.
[26]
Tulane University School of Public Health and Tropical Medicine.
[27]
Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI.
[28]
Seoul National University.
[29]
11. Institute of Environmental Medicine, Karolinska Institute, Stockholm.
[30]
Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio.
[31]
University of Newcastle.
[32]
University of Cambridge.
[33]
Fimlab Laboratories and Finnish Cardiovascular Research Center.
[34]
Inserm.
[35]
University of Lille, Inserm, Institut Pasteur de Lille.
[36]
Nagoya University Graduate School of Medicine.
[37]
Institute for Maternal and Child Health-IRCCS.
[38]
University of Groningen, University Medical Center Groningen.
[39]
Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR.
[40]
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai.
[41]
University of Alabama at Birmingham.
[42]
Institute for Maternal and Child Health - IRCCS, Burlo Garofolo.
[43]
University of Maryland.
[44]
The University of Edinburgh.
[45]
University of Regensburg, University Hospital Regensburg.
[46]
Queen Mary University of London.
[47]
University of Trieste.
[48]
Japan Institute for Health Security.
[49]
National University of Singapore and National University Health System, Singapore.
[50]
Boston University.
[51]
University of Tartu.
[52]
University of Lausanne.
[53]
University Medical Center Groningen.
[54]
Tsinghua University.
[55]
University Medicine Greifswald & University of Greifswald.
[56]
Massachusetts General Hospital.
[57]
Monash University.
[58]
University Hospital Regensburg.
[59]
Tulane University.
[60]
Universitätsklinikum Regensburg.
[61]
Medical College of Wisconsin.
[62]
Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR.
[63]
Johns Hopkins University.
[64]
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
[65]
National Human Genome Research Institute.
[66]
Harbor-UCLA Medical Center.
[67]
Lille University Hospital.
[68]
University of Kelaniya.
[69]
Department of Veterans Affairs.
[70]
University of Eastern Finland.
[71]
University of Wisconsin School of Medicine and Public Health.
[72]
University of North Carolina at Chapel Hill.
[73]
Washington University School of Medicine.
[74]
University of Texas Southwestern Medical Center.
[75]
Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus.
[76]
VA Tennessee Valley Healthcare System.
[77]
University of Utah School of Medicine.
[78]
University of Alabama at Birmingham School of Public Health.
[79]
Tampere University.
[80]
University of Helsinki, Helsinki University Hospital, Finnish Institute for Health and Welfare.
[81]
University of Split.
[82]
Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
[83]
University of Sao Paulo, Laboratory of Genetics and Molecular Cardiology.
[84]
National Institute on Aging, National Institutes of Health.
[85]
National Heart, Lung, and Blood Institute, National Institutes of Health.
[86]
Genome Institute of Singapore.
[87]
The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.
[88]
Amsterdam UMC, Vrije Universiteit/GGZ inGeest.
[89]
The University of Sydney.
[90]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
[91]
Department of Epidemiology, School of Public Health, University of Michigan.
[92]
Institute for Maternal and Child Health - IRCCS "Burlo Garofolo".
[93]
University of California Irvine.
[94]
Turku University Hospital and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku.
[95]
University of the Witwatersrand.
[96]
Edinburgh University.
[97]
Singapore Eye Research Institute.
[98]
Medical University of Graz.
[99]
University of Newcastle and the Hunter Medical Research Institute.
[100]
University of Copenhagen.
[101]
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
[102]
University of Trieste/Institute for Maternal and Child Health, I.R.C.C.S. "Burlo Garofolo".
[103]
University of Glasgow.
[104]
Children's Hospital of Philadelphia.
[105]
Saw Swee Hock School of Public Health, National University of Singapore and National University Health System.
[106]
UMCG.
[107]
George Washington University.
[108]
Lausanne University Hospital and University of Lausanne.
[109]
Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
[110]
University Medicine Greifswald.
[111]
Huazhong University of Science and Technology, Tongji Medical College.
[112]
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London.
[113]
Kurume University School of Medicine.
[114]
Institute for Translational Genomics and Population Sciences/The Lundquist Institute at Harbor-UCLA Medical Center.
[115]
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement.
[116]
VUMC.
[117]
Universidad Peruana Cayetano Heredia.
[118]
Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé.
[119]
National University of Singapore.
[120]
Istitute of Genetics and Biophysics A. Buzzati-Traverso - CNR.
[121]
Institute for Maternal and Child Health - IRCCS.
[122]
Lothian Birth Cohorts, Department of Psychology, University of Edinburgh.
[123]
Department of Internal Medicine B (Cardiology).
[124]
University of North Carolina.
[125]
IRCCS-Burlo Garofolo / University of Trieste.
[126]
Icelandic Heart Association.
[127]
Department of Genetic Epidemiology, University of Regensburg.
[128]
Hunter Medical Research Institute.
[129]
28. Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine.
[130]
Rothschild Foundation Hospital, Institut Français de Myopie.
[131]
National Center for Global Health and Medicine.
[132]
Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester.
[133]
University of Illinois at Chicago.
[134]
University of Colorado at Anschutz.
[135]
Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University.
[136]
O'Donnell School of Public Health, UT Southwestern Medical Center.
[137]
Boston University School of Public Health.
[138]
Amsterdam UMC.
[139]
Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System.
[140]
Faculty of Medicine, University of Split.
[141]
Cardiovascular Health Research Unit.
[142]
Kuopio Research Institute of Exercise Medicine.
[143]
National Institutes of health.
[144]
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center.
[145]
Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, Scotland, UK.
[146]
Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Medical University of Graz, Austria.
[147]
University Regensburg.
[148]
RIKEN Center for Integrative Medical Sciences.
[149]
Oxford University.
[150]
University of Southern California.
[151]
New York University.
[152]
University of Maryland School of Medicine.
[153]
Broad Institute.
[154]
Washington University in St. Louis.
[155]
Queen Mary University.
[156]
DOI
10.21203/rs.3.rs-9283196/v1
PMID
41960332
发布时间
2026-04-30
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