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Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

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第一作者: Mary,Feitosa
第一单位: Washington School of Medicine.
作者: Mary,Feitosa [1] ; Karen,Schwander [2] ; Clint,Miller [3] ; Aldi,Kraja [4] ; Amy,Bentley [5] ; Michael,Brown [6] ; Hannah,de Hesselle [7] ; Raymond,Noordam [8] ; Songmi,Lee [9] ; Pavithra,Nagarajan [10] ; Heming,Wang [11] ; Ayush,Giri [12] ; Farrah,Ammous [13] ; Traci,Bartz [14] ; Chiara,Batini [15] ; Jean-Tristan,Brandenburg [16] ; Max,Breyer [17] ; Heather,Cordell [18] ; Janie,Corley [19] ; Latchezar,Dimotrov [20] ; Anh,Do [10] ; Jiawen,Du [21] ; Franco,Giulianini [22] ; Christopher,Grace [23] ; Valborg,Gudmundsdottir [6] ; Xiuqing,Guo [7] ; Sarah,Harris [24] ; Natalie,Hasbani [25] ; Janina,Herold [10] ; Keiko,Hikino [26] ; Edith,Hofer [27] ; Andrea,Horimoto [28] ; Fang-Chi,Hsu [29] ; Zhijie,Huang [30] ; Anne,Jackson [31] ; Chang Hoon,Kang [32] ; Federica,Laguzzi [33] ; Timo,Lakka [34] ; Christophe,Lefevre [35] ; Jian'an,Luan [36] ; Leo-Pekka,Lyytikäinen [37] ; Aline,Meirhaeghe [38] ; Manon,Muntaner [39] ; Masahiro,Nakatochi [40] ; Giuseppe Giovanni,Nardone [41] ; Ilja,Nolte [42] ; Teresa,Nutile [43] ; Nicholette,Palmer [44] ; Amit,Patki [45] ; Alessandro,Pecori [46] ; Varun,Rao [47] ; Anne,Richmond [48] ; Mercedes,Richter [13] ; Mihir,Sanghvi [49] ; Aurora,Santin [50] ; Heather,Stringham [51] ; Fumihiko,Takeuchi [52] ; Ye An,Tan [53] ; Jingxian,Tang [8] ; Maris,Teder-Laving [54] ; Olga,Trofimova [55] ; Stella,Trompet [42] ; Peter,van der Most [8] ; Ya Xing,Wang [13] ; Zhe,Wang [56] ; Yujie,Wang [57] ; Wenyi,Wang [58] ; Erin,Ware [12] ; Stefan,Weiss [4] ; Kenneth,Westerman [4] ; Chenglong,Yu [39] ; Wanying,Zhu [59] ; Md Abu Yusuf,Ansari [60] ; Pramod,Anugu [14] ; Anna,Argoty-Pantoja [61] ; John,Attia [14] ; Bernhard,Banas [62] ; Lydia,Bazzano [18] ; Joshua,Bis [63] ; Carsten,Boger [64] ; Jennifer,Brody [65] ; Ulrich,Broeckel [66] ; Harry,Campbell [67] ; Archie,Campbell [15] ; Pasqualina,Cennamo [13] ; William,Checkley [68] ; Miao-Li,Chee [69] ; Guanjie,Chen [12] ; Yii-Der,Chen [70] ; Kayesha,Coley [25] ; Stacey,Collins [13] ; Jean,Dallongeville [71] ; Hithanadura Janaka,de Silva [72] ; Charles,Dupont [21] ; Todd,Edwards [7] ; Christian,Enzinger [73] ; Jessica,Faul [74] ; Lilian Fernandes,Silva [75] ; Adam,Gepner [76] ; Anuj,Goel [13] ; Mathias,Gorski [77] ; Mariaelisa,Graff [78] ; C Charles,Gu [79] ; Jiang,He [80] ; Sami,Heikkinen [13] ; Erin,Hill-Burns [29] ; Adriana,Hung [81] ; Steven,Hunt [82] ; Marguerite,Irvin [83] ; Mika,Kähönen [84] ; Sharon,Kardia [85] ; Minjung,Kho [86] ; Heikki,Koistinen [87] ; Ivana,Kolčić [88] ; Pirjo,Komulainen [58] ; José Eduardo,Krieger [89] ; Lenore,Launer [90] ; Daniel,Levy [91] ; Jianjun,Liu [71] ; Joseph,McCormick [92] ; John,McNeil [93] ; Yuri,Milaneschi [94] ; Jaime,Miranda [95] ; Kari,North [96] ; Anniina,Oravilahti [74] ; Alison,Pattie [97] ; Patricia,Peyser [8] ; Giulia,Pianigiani [40] ; Leslie,Raffel [18] ; Olli,Raitakari [98] ; Michele,Ramsay [16] ; Salil,Redkar [99] ; Paul,Redmond [13] ; Paul,Ridker [100] ; Frits,Rosendaal [18] ; Daniela,Ruggiero [101] ; Tom,Russ [102] ; Charumathi,Sabanayagam [98] ; Alyssa,Scartozzi [103] ; Reinhold,Schmidt [104] ; Laura,Scott [105] ; Rodney,Scott [15] ; Susan,Shenkin [106] ; Roelof,Smit [48] ; Jennifer A,Smith [107] ; Zhi,Da Soh [12] ; Beatrice,Spedicati [108] ; David,Stott [109] ; Quan,Sun [110] ; Gerald,Sze [111] ; E Shyong,Tai [112] ; Paola,Tesolin [113] ; Rima,Triatin [69] ; Nataraja Sarma,Vaitinadin [8] ; Rob,van Dam [98] ; Julien,Vaucher [114] ; Uwe,Völker [115] ; Henry,Völzke [114] ; Chaolong,Wang [7] ; Helen,Warren [116] ; Rajitha,Wickremasinghe [117] ; Ko,Willems van Dijk [53] ; Cancan,Xue [118] ; Ken,Yamamoto [13] ; Jie,Yao [119] ; Mitsuhiro,Yokota [26] ; Martina,Zimmermann [10] ; Philippe,Amouyel [120] ; Jennifer,Below [121] ; Sven,Bergmann [122] ; Antonio,Bernabe-Ortiz [123] ; Michael,Boehnke [68] ; Palwende,Boua [18] ; LifeLines Cohort study [124] ; Donald,Bowden [4] ; Daniel,Chasman [125] ; Ching-Yu,Cheng [19] ; Marina,Ciullo [126] ; Maria Pina,Concas [93] ; Simon R,Cox [127] ; Luc,Dauchet [128] ; Ian,Deary [129] ; Stephan,Felix [130] ; Ervin,Fox [15] ; Nora,Franceschini [131] ; Barry,Freedman [8] ; Paolo,Gasparini [52] ; Giorgia,Girotto [132] ; Vilmundur,Gudnason [133] ; Caroline,Hayward [134] ; Iris,Heid [71] ; Elizabeth,Holliday [58] ; Sahoko,Ichihara [135] ; Catherine,John [30] ; Jost,Jonas [29] ; J Wouter,Jukema [136] ; Mart,Kals [137] ; Norihiro,Kato [138] ; Bernard,Keavney [101] ; Tanika,Kelly [139] ; Markku,Laakso [140] ; Paul,Lacaze [141] ; Leslie,Lange [142] ; Karin,Leander [143] ; Seunggeun,Lee [144] ; Terho,Lehtimäki [145] ; Changwei,Li [146] ; Ching-Ti,Liu [147] ; Ruth,Loos [120] ; Brenda,Penninx [54] ; Alexandre,Pereira [148] ; Ozren,Polasek [149] ; Bruce,Psaty [26] ; Rainer,Rauramaa [33] ; Charles,Rotimi [150] ; Jerome,Rotter [13] ; Igor,Rudan [73] ; Helena,Schmidt [13] ; Xueling,Sim [151] ; Harold,Snieder [6] ; Klaus,Stark [6] ; Chikashi,Terao [152] ; Lynne,Wagenknecht [153] ; Nicholas,Wareham [154] ; Hugh,Watkins [6] ; David,Weir [74] ; Kristin,Young [155] ; Wei,Zhao [156] ; William,Gauderman [2] ; Alanna,Morrison [148] ; Myriam,Fornage ; Han,Chen ; Jeffrey,O'Connell ; Alisa,Manning ; Paul,de Vries ; Lisa,de Las Fuentes ; Dabeeru,Rao ; Patricia,Munroe ; Michael,Province ; Thomas,Winkler
作者单位: Washington School of Medicine. [1] Washington University. [2] University of Virginia. [3] University of Mississippi Medical Center. [4] National Institutes of Health, NHGRI. [5] The University of Texas Health Science Center at Houston. [6] University of Regensburg. [7] Leiden University Medical Center. [8] University of Texas Health Science Center at Houston, McGovern Medical School. [9] Brigham and Women's Hospital. [10] Brigham and Women's Hospital; Harvard Medical School. [11] Vanderbilt University Medical Center. [12] University of Michigan. [13] University of Washington. [14] University of Leicester. [15] Vanderbilt University School of Medicine. [16] Newcastle University. [17] University of Edinburgh. [18] Wake Forest University School of Medicine. [19] Washington University School of Medicine, St. Louis, MO, USA. [20] Radcliffe Department of Medicine, University of Oxford. [21] Faculty of Medicine, University of Iceland. [22] Lothian Birth Cohorts, Dept. Psychology. [23] RIKEN. [24] Medical University Graz. [25] Wake Forest School of Medicine. [26] Tulane University School of Public Health and Tropical Medicine. [27] Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI. [28] Seoul National University. [29] 11. Institute of Environmental Medicine, Karolinska Institute, Stockholm. [30] Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio. [31] University of Newcastle. [32] University of Cambridge. [33] Fimlab Laboratories and Finnish Cardiovascular Research Center. [34] Inserm. [35] University of Lille, Inserm, Institut Pasteur de Lille. [36] Nagoya University Graduate School of Medicine. [37] Institute for Maternal and Child Health-IRCCS. [38] University of Groningen, University Medical Center Groningen. [39] Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR. [40] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai. [41] University of Alabama at Birmingham. [42] Institute for Maternal and Child Health - IRCCS, Burlo Garofolo. [43] University of Maryland. [44] The University of Edinburgh. [45] University of Regensburg, University Hospital Regensburg. [46] Queen Mary University of London. [47] University of Trieste. [48] Japan Institute for Health Security. [49] National University of Singapore and National University Health System, Singapore. [50] Boston University. [51] University of Tartu. [52] University of Lausanne. [53] University Medical Center Groningen. [54] Tsinghua University. [55] University Medicine Greifswald & University of Greifswald. [56] Massachusetts General Hospital. [57] Monash University. [58] University Hospital Regensburg. [59] Tulane University. [60] Universitätsklinikum Regensburg. [61] Medical College of Wisconsin. [62] Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR. [63] Johns Hopkins University. [64] Singapore Eye Research Institute, Singapore National Eye Centre, Singapore. [65] National Human Genome Research Institute. [66] Harbor-UCLA Medical Center. [67] Lille University Hospital. [68] University of Kelaniya. [69] Department of Veterans Affairs. [70] University of Eastern Finland. [71] University of Wisconsin School of Medicine and Public Health. [72] University of North Carolina at Chapel Hill. [73] Washington University School of Medicine. [74] University of Texas Southwestern Medical Center. [75] Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus. [76] VA Tennessee Valley Healthcare System. [77] University of Utah School of Medicine. [78] University of Alabama at Birmingham School of Public Health. [79] Tampere University. [80] University of Helsinki, Helsinki University Hospital, Finnish Institute for Health and Welfare. [81] University of Split. [82] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [83] University of Sao Paulo, Laboratory of Genetics and Molecular Cardiology. [84] National Institute on Aging, National Institutes of Health. [85] National Heart, Lung, and Blood Institute, National Institutes of Health. [86] Genome Institute of Singapore. [87] The University of Texas Health Science Center at Houston (UTHealth) School of Public Health. [88] Amsterdam UMC, Vrije Universiteit/GGZ inGeest. [89] The University of Sydney. [90] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC. [91] Department of Epidemiology, School of Public Health, University of Michigan. [92] Institute for Maternal and Child Health - IRCCS "Burlo Garofolo". [93] University of California Irvine. [94] Turku University Hospital and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku. [95] University of the Witwatersrand. [96] Edinburgh University. [97] Singapore Eye Research Institute. [98] Medical University of Graz. [99] University of Newcastle and the Hunter Medical Research Institute. [100] University of Copenhagen. [101] Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. [102] University of Trieste/Institute for Maternal and Child Health, I.R.C.C.S. "Burlo Garofolo". [103] University of Glasgow. [104] Children's Hospital of Philadelphia. [105] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System. [106] UMCG. [107] George Washington University. [108] Lausanne University Hospital and University of Lausanne. [109] Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany. [110] University Medicine Greifswald. [111] Huazhong University of Science and Technology, Tongji Medical College. [112] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. [113] Kurume University School of Medicine. [114] Institute for Translational Genomics and Population Sciences/The Lundquist Institute at Harbor-UCLA Medical Center. [115] Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement. [116] VUMC. [117] Universidad Peruana Cayetano Heredia. [118] Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé. [119] National University of Singapore. [120] Istitute of Genetics and Biophysics A. Buzzati-Traverso - CNR. [121] Institute for Maternal and Child Health - IRCCS. [122] Lothian Birth Cohorts, Department of Psychology, University of Edinburgh. [123] Department of Internal Medicine B (Cardiology). [124] University of North Carolina. [125] IRCCS-Burlo Garofolo / University of Trieste. [126] Icelandic Heart Association. [127] Department of Genetic Epidemiology, University of Regensburg. [128] Hunter Medical Research Institute. [129] 28. Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine. [130] Rothschild Foundation Hospital, Institut Français de Myopie. [131] National Center for Global Health and Medicine. [132] Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester. [133] University of Illinois at Chicago. [134] University of Colorado at Anschutz. [135] Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University. [136] O'Donnell School of Public Health, UT Southwestern Medical Center. [137] Boston University School of Public Health. [138] Amsterdam UMC. [139] Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System. [140] Faculty of Medicine, University of Split. [141] Cardiovascular Health Research Unit. [142] Kuopio Research Institute of Exercise Medicine. [143] National Institutes of health. [144] The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. [145] Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, Scotland, UK. [146] Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Medical University of Graz, Austria. [147] University Regensburg. [148] RIKEN Center for Integrative Medical Sciences. [149] Oxford University. [150] University of Southern California. [151] New York University. [152] University of Maryland School of Medicine. [153] Broad Institute. [154] Washington University in St. Louis. [155] Queen Mary University. [156]
DOI 10.21203/rs.3.rs-9283196/v1
PMID 41960332
发布时间 2026-04-30
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