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Interpretable deep generative ensemble learning for single-cell omics with Hydra.

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第一作者： Manoj M,Wagle

第一单位： School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Camperdown, NSW, Australia.;Computational Systems Biology Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.;Sydney Precision Data Science Center, The University of Sydney, Camperdown, NSW, Australia.;Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.

作者： Manoj M,Wagle ^[1] ; Chunlei,Liu ^[2] ; Zunpeng,Liu ^[3] ; Yongheng,Wang ^[3] ; Manolis,Kellis ^[3] ; Ellis,Patrick ^[4] ; Pengyi,Yang ^[5]

作者单位： School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Camperdown, NSW, Australia.;Computational Systems Biology Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia.;Sydney Precision Data Science Center, The University of Sydney, Camperdown, NSW, Australia.;Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA. ^[1] School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Camperdown, NSW, Australia.;Computational Systems Biology Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. ^[2] Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.;Computational Biology Group, The Broad Institute of MIT and Harvard, Cambridge, MA, USA. ^[3] School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Camperdown, NSW, Australia. ellis.patrick@sydney.edu.au.;Sydney Precision Data Science Center, The University of Sydney, Camperdown, NSW, Australia. ellis.patrick@sydney.edu.au.;Charles Perkins Center, The University of Sydney, Camperdown, NSW, Australia. ellis.patrick@sydney.edu.au.;Center for Cancer Research, Westmead Institute for Medical Research, Westmead, NSW, Australia. ellis.patrick@sydney.edu.au. ^[4] School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Camperdown, NSW, Australia. pengyi.yang@sydney.edu.au.;Computational Systems Biology Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW, Australia. pengyi.yang@sydney.edu.au.;Sydney Precision Data Science Center, The University of Sydney, Camperdown, NSW, Australia. pengyi.yang@sydney.edu.au.;Charles Perkins Center, The University of Sydney, Camperdown, NSW, Australia. pengyi.yang@sydney.edu.au. ^[5]

医学主题词单细胞分析(Single-Cell Analysis);人类(Humans);计算生物学(Computational Biology);基因组学(Genomics)

DOI 10.1038/s44320-026-00208-7

PMID 41965454

发布时间 2026-07-02

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