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Peroxisome-derived and liver-specific hydroxyacid oxidase 1-mediated hydrogen peroxide promotes ferroptosis by augmenting peroxisomal ROS.

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第一作者: Xintong,Peng
第一单位: Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Ministry of Education, Department of Pathology, Xiangya Hospital, Central South University, 410078 Changsha, China; National Health Commission Key Laboratory of Carcinogenesis, Cancer Research Institute, Xiangya School of Basic Medical Sciences, Central South University, 410078 Changsha, China.
作者: Xintong,Peng [1] ; Yanling,Zhou [2] ; Jielin,Chen [3] ; Zuli,Wang [1] ; Xin,Peng [3] ; Haiyan,Wang [1] ; Long,Shu [1] ; Na,Liu [3] ; Yao,Long [1] ; Li,Linghu [1] ; Zewen,Zhang [1] ; Yuanhao,Peng [1] ; Yuzheng,Zhao [4] ; Desheng,Xiao [5] ; Ying,Shi [6] ; Shuang,Liu [7] ; Yongguang,Tao [8]
作者单位: Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Ministry of Education, Department of Pathology, Xiangya Hospital, Central South University, 410078 Changsha, China; National Health Commission Key Laboratory of Carcinogenesis, Cancer Research Institute, Xiangya School of Basic Medical Sciences, Central South University, 410078 Changsha, China. [1] Department of Oncology, Institute of Medical Sciences, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, 410008 Changsha, China. [2] Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Ministry of Education, Department of Pathology, Xiangya Hospital, Central South University, 410078 Changsha, China. [3] Optogenetics & Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai 200237, China. [4] Department of Pathology, Xiangya Hospital, Central South University, Changsha Hunan 410008, China. Electronic address: xdsh96@csu.edu.cn. [5] Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Ministry of Education, Department of Pathology, Xiangya Hospital, Central South University, 410078 Changsha, China; National Health Commission Key Laboratory of Carcinogenesis, Cancer Research Institute, Xiangya School of Basic Medical Sciences, Central South University, 410078 Changsha, China. Electronic address: yingshi@csu.edu.cn. [6] Department of Oncology, Institute of Medical Sciences, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, 410008 Changsha, China. Electronic address: shuangliu2016@csu.edu.cn. [7] Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Ministry of Education, Department of Pathology, Xiangya Hospital, Central South University, 410078 Changsha, China; National Health Commission Key Laboratory of Carcinogenesis, Cancer Research Institute, Xiangya School of Basic Medical Sciences, Central South University, 410078 Changsha, China; Department of Pathology, Xiangya Hospital, Central South University, Changsha Hunan 410008, China; Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China. Electronic address: taoyong@csu.edu.cn. [8]
DOI 10.1016/j.jare.2026.04.038
PMID 41990971
发布时间 2026-04-25
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Journal of advanced research

Journal of advanced research

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