首页> Journal of translational medicine> Deciphering immune and cellular reprogramming during the progression from inflammatory bowel disease to colorectal cancer using multi-omics single-cell and spatial transcriptomics.

Deciphering immune and cellular reprogramming during the progression from inflammatory bowel disease to colorectal cancer using multi-omics single-cell and spatial transcriptomics.

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第一作者： Seyed Taleb,Hosseini

第一单位： Immunogenetics Research Center, Mazandaran University of Medical Sciences, Sari, Iran.;Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran.

作者： Seyed Taleb,Hosseini ^[1] ; Kimia,AminianToosi ^[2] ; Farkhondeh,Nemati ^[3] ; Roya,BishehKolaei ^[4] ; Youping,Deng ^[5]

作者单位： Immunogenetics Research Center, Mazandaran University of Medical Sciences, Sari, Iran.;Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran. ^[1] Clinical Research Development Unit, Faculty of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. ^[2] Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran. ^[3] Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran. rbishe@gmail.com. ^[4] Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, 96813, USA. dengy@hawaii.edu. ^[5]

关键词 Colorectal cancer Crohn’s disease Inflammatory bowel disease Multi-omics Single-cell Spatial transcriptomics Ulcerative colitis

DOI 10.1186/s12967-026-08158-2

PMID 42001187

发布时间 2026-06-25

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