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LIF-Induced Tumor Plasticity Establishes an Immunosuppressive Myeloid Niche in LKB1-Mutant Lung Cancer.

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第一作者: Ray,Pillai
第一单位: Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, New York.;Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Division of Pulmonary and Critical Care Medicine, Department of Medicine, VA New York Harbor Healthcare System, New York, New York.
作者单位: Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, New York.;Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Division of Pulmonary and Critical Care Medicine, Department of Medicine, VA New York Harbor Healthcare System, New York, New York. [1] Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, New York. [2] Applied Bioinformatics Laboratories, New York University Langone Health, New York, New York.;Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, New York. [3] Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira, Brazil. [4] Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Department of Basic Oncology, Hacettepe University, Ankara, Turkey. [5] Department of Pathology, New York University Grossman School of Medicine, New York, New York. [6] Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, New York. [7] Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts. [8] Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, New York. [9] Department of Genetics and Genomic Sciences, Center for Transformative Disease Modeling, Tisch Cancer Institute, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York. [10] Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, New York.;Department of Microbiology, New York University Langone Health, New York, New York. [11] Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York. [12] Division of Hematology & Medical Oncology, Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York. [13] Experimental Pathology Research Laboratory (RRID:SCR_017928), New York University Langone Health, New York, New York. [14] Celsius Therapeutics, Cambridge, Massachusetts. [15] Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, New York.;Division of Pulmonary and Critical Care Medicine, Department of Medicine, VA New York Harbor Healthcare System, New York, New York. [16] Department of Biochemistry, Federal University of São Paulo (UNIFESP), São Paulo, Brazil. [17] Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.;Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York. [18] Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, New York.;Department of Microbiology, New York University Langone Health, New York, New York. [19] Department of Cardiothoracic Surgery, New York University Langone Health, New York, New York. [20] Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, New York.;Department of Biochemistry & Molecular Pharmacology, New York University Grossman School of Medicine, New York, New York. [21] Department of Pathology, New York University Grossman School of Medicine, New York, New York.;Applied Bioinformatics Laboratories, New York University Langone Health, New York, New York. [22]
DOI 10.1158/2159-8290.CD-25-0470
PMID 42008781
发布时间 2026-04-20
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