首页> Cancer & metabolism> SENP1 drives de novo cholesterogenesis via disrupting SUMOylation-mediated SREBP2-FBXW7 interaction.

SENP1 drives de novo cholesterogenesis via disrupting SUMOylation-mediated SREBP2-FBXW7 interaction.

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第一作者： Chun,Yang

第一单位： Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.

作者： Chun,Yang ^[1] ; Qingbo,Wang ^[1] ; Bangmin,Han ^[2] ; Xun,Shangguan ^[3]

作者单位： Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. ^[1] Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. hanbm@163.com. ^[2] Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. xun.shangguan@shgh.cn. ^[3]

关键词 Cholesterogenesis Prostate cancer SENP1 SREBP2 SUMOylation

DOI 10.1186/s40170-026-00434-5

PMID 42015300

发布时间 2026-06-03

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2026年14卷1期

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SENP1 drives de novo cholesterogenesis via disrupting SUMOylation-mediated SREBP2-FBXW7 interaction.

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SENP1 drives de novo cholesterogenesis via disrupting SUMOylation-mediated SREBP2-FBXW7 interaction.

Cancer & metabolism

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