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Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP).

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第一作者: Madiha,Hashmi
第一单位: Department of Critical Care Medicine, Ziauddin University-Karachi, Sindh, Pakistan.
作者: Madiha,Hashmi [1] ; Rashan,Haniffa [2] ; Deva,Jayakumar [3] ; Abigail,Beane [2] ; Elizabeth,Lorenzi [4] ; Lindsay R,Berry [4] ; Muhammad,Nasir Khoso [5] ; Quratul,Ain Khan [6] ; Ashok,Kumar [7] ; Aneela,Altaf Kidwai [8] ; Thomas E,Hills [9] ; Djillali,Annane [10] ; Diptesh,Aryal [11] ; Carly,Au [12] ; Kenneth,Baillie [13] ; Richard,Beasley [9] ; Janis,Best-Lane [14] ; Marc,Bonten [15] ; Charlotte A,Bradbury [16] ; Frank M,Brunkhorst [17] ; Aidan,Burrell [18] ; Meredith,Buxton [19] ; Maurizio,Cecconi [20] ; Allen C,Cheng [21] ; Matthew E,Cove [22] ; Menno,de Jong [23] ; Michelle A,Detry [4] ; Eamon,Duffy [24] ; Lise J,Estcourt [25] ; Mark,Fitzgerald [4] ; Rob,Fowler [26] ; Herman,Goossens [27] ; Cameron,Green [28] ; Leanne M C,Hays [29] ; Alisa M,Higgins [30] ; David T,Huang [31] ; Nao,Ichihara [32] ; Sabin,Koirala [33] ; François,Lamontagne [34] ; Patrick R,Lawler [35] ; Roger J,Lewis [4] ; Edward,Litton [36] ; Niamh,Mahon [29] ; John C,Marshall [37] ; Daniel F,McAuley [38] ; Anna,McGlothlin [4] ; Shay,McGuinness [24] ; Zoe K,McQuilten [28] ; Bryan J,McVerry [39] ; Paul R,Mouncey [12] ; Susan,Morpeth [40] ; Mihai,Netea [41] ; Katrina,Orr [42] ; Rachael L,Parke [43] ; Jane C,Parker [28] ; Asad,Patanwala [44] ; Svenja,Peters [45] ; Luis Felipe,Reyes [46] ; Kathryn M,Rowan [12] ; Hiroki,Saito [47] ; Christina T,Saunders [4] ; Marlene,Santos [48] ; Christopher W,Seymour [31] ; Manu,Shankar-Hari [49] ; Vanessa,Singh [30] ; Matthew,Slater [50] ; Paul A,Tambyah [51] ; Steven Y C,Tong [52] ; Alexis F,Turgeon [53] ; Anne M,Turner [9] ; Frank,van de Veerdonk [54] ; Sebastian,Weis [55] ; Ryan,Zarychanski [56] ; Colin J,McArthur [24] ; Derek C,Angus [31] ; Scott M,Berry [4] ; Anthony C,Gordon [57] ; Lennie P G,Derde [58] ; Steve A,Webb [59] ; Srinivas,Murthy [60] ; Yaseen,Arabi [61] ; Alistair D,Nichol [62] ; and the Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP) Investigators
作者单位: Department of Critical Care Medicine, Ziauddin University-Karachi, Sindh, Pakistan. [1] Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.;Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom. [2] Department of Critical Care, Dr Kamakshi Memorial Hospital, Chennai, Tamil Nadu, India. [3] Berry Consultants, Austin, TX. [4] South City Hospital, Karachi, Pakistan. [5] Critical Care, North Nazimabad Campus, Dr Ziauddin Group of Hospitals, Karachi, Pakistan. [6] Department of Chest Medicine and Critical Care, Ziauddin University, Karachi, Sindh, Pakistan. [7] Department of Medicine, Abbasi Shaheed Hospital, Nazimabad, Karachi, Pakistan. [8] Medical Research Institute, Wellington, New Zealand. [9] Service de Réanimation médicale et unité de ventilation à domicile, centre de référence neuromusculaire GNHM, CHU Raymond Poincaré, APHP, Université de Versailles Saint Quentin en Yvelines, Garches, France. [10] Nepal Intensive Care Research Foundation, Kathmandu, Nepal. [11] Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, United Kingdom. [12] Centre for Inflammation Research, Deanery of Clinical Sciences, University of Edinburgh, Midlothian, United Kingdom. [13] Division of Anaesthetics, Pain Medicine, and Intensive Care, Imperial College London, London, United Kingdom. [14] Department of Medical Microbiology, University Medical Center, Utrecht, The Netherlands.;Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands. [15] University of Bristol, Bristol, United Kingdom. [16] Jena University Hospital, Jena, Germany. [17] Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.;Department of Intensive Care and Hyperbaric Medicine, The Alfred, Melbourne, VIC, Australia. [18] Global Coalition for Adaptive Research, Larkspur, CA. [19] Department of Anesthesiology and Intensive Care, IRCCS Humanitas Research Hospital, Milan, Italy. [20] Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia.;Infectious Diseases Unit, Alfred Hospital, Melbourne, VIC, Australia. [21] National University of Singapore, Singapore. [22] Department of Medical Microbiology, University Medical Center, Utrecht, The Netherlands. [23] Auckland City Hospital, Auckland, New Zealand. [24] University of Oxford, Oxford, United Kingdom. [25] Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.;Department of Medicine, University of Toronto, Toronto, ON, Canada. [26] Medical Microbiology, Vaccine & Infectious Diseases Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium. [27] Monash University, Melbourne, VIC, Australia. [28] University College Dublin Clinical Research Centre, St Vincent's University Hospital, Dublin, Ireland. [29] Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia. [30] University of Pittsburgh, Pittsburgh, PA. [31] The University of Tokyo, Bunkyo-ku, Tokyo, Japan. [32] Department of Pulmonary, Critical Care and Sleep Medicine, Hospital for Advanced Medicine and Surgery, Kathmandu, Nepal. [33] Universite de Sherbrooke, Sherbrooke, QC, Canada. [34] McGill University Faculty of Medicine, Montreal, QC, Canada. [35] The University of Western Australia, Perth, WA, Australia. [36] University of Toronto, Toronto, Ontario, Canada. [37] ICU, QUB, Belfast, United Kingdom.;Centre for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom. [38] Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, PA. [39] Middlemore Hospital, Auckland, New Zealand. [40] Radboud Universitair Medisch Centrum, Nijmegen, The Netherlands. [41] Fiona Stanley Hospital, Murdoch, WA, Australia. [42] The University of Auckland, Auckland, New Zealand. [43] Auckland City Hospital, Auckland, New Zealand.;Royal Prince Alfred Hospital, Camperdown, NSW, Australia. [44] European Clinical Research Alliance on Infectious Diseases (Ecraid), Utrecht, The Netherlands. [45] Universidad de La Sabana, Chia, Colombia. [46] St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan. [47] Unity Health Toronto, Toronto, ON, Canada. [48] Centre for Inflammation Research, The University of Edinburgh College of Medicine and Veterinary Medicine, Edinburgh, United Kingdom. [49] Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia. [50] Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. [51] The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia. [52] Universite Laval, Quebec, QC, Canada. [53] Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. [54] Institute for Infectious Disease and Infection Control, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.;Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.;Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Jena, Germany. [55] University of Manitoba, Winnipeg, MB, Canada. [56] Imperial College London, London, United Kingdom. [57] Intensive Care Center, University Medical Centre, Utrecht, The Netherlands. [58] Monash University, Clayton, VIC, Australia. [59] The University of British Columbia, Vancouver, BC, Canada. [60] Critical Care, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia. [61] Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.;University College Dublin Clinical Research Centre, St Vincent's University Hospital, Dublin, Ireland. [62]
DOI 10.1097/CCM.0000000000007134
PMID 42101205
发布时间 2026-05-14
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