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A Comprehensive Immune Checkpoint Phenotype Predicts Response and Survival to PD-1 Blockade in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma.

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第一作者： Mathias,Fiedler

第一单位： Department of Oral and Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany.;Department of Oral and Maxillofacial Surgery, Center for Medical Biotechnology, University Hospital Regensburg, Regensburg, Germany.

作者： Mathias,Fiedler ^[1] ; Lea,Baumann ^[2] ; Jonas,Eichberger ^[1] ; Maximilian,Gottsauner ^[3] ; Johannes G,Schuderer ^[3] ; Daniela,Schulz ^[1] ; Johannes K,Meier ^[3] ; Richard J,Bauer ^[1] ; Hendrik,Poeck ^[4] ; Matthias,Grube ^[4] ; Michael,Gerken ^[5] ; Torsten E,Reichert ^[3] ; Florian,Weber ^[6] ; Tobias,Ettl ^[1]

作者单位： Department of Oral and Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany.;Department of Oral and Maxillofacial Surgery, Center for Medical Biotechnology, University Hospital Regensburg, Regensburg, Germany. ^[1] Department of Oral and Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany.;Institute of Pathology, University of Regensburg, Regensburg, Germany. ^[2] Department of Oral and Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany. ^[3] Department of Internal Medicine III, Hematology & Internal Oncology, University Hospital Regensburg, Regensburg, Germany. ^[4] Center of Tumor Registry, University of Regensburg, Regensburg, Germany. ^[5] Institute of Pathology, University of Regensburg, Regensburg, Germany. ^[6]

关键词 PD‐1 blockade head and neck squamous cell carcinoma immune checkpoint inhibition immunotherapy biomarkers tumor immune microenvironment

DOI 10.1002/hed.70313

PMID 42108192

发布时间 2026-05-10

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