第一单位：
Garvan Institute of Medical Research, Sydney, NSW, Australia.
作者：
Kristine J,Fernandez [1]
;
Ghazal,Sultani [2]
;
Max,Nobis [3]
;
Brian,Gloss [4]
;
Leila,Eshraghi [2]
;
Amy E,McCart Reed [5]
;
Sarah,Alexandrou [2]
;
Christine,Lee [1]
;
Daniel L,Roden [2]
;
Emily I,Jones [6]
;
Maryam Hasha,Simad [2]
;
Ewan K A,Millar [7]
;
Nenad,Bartonicek [1]
;
Samantha R,Oakes [8]
;
Fatima,Valdes-Mora [9]
;
Yolanda,Colino-Sanguino [10]
;
Ellie T Y,Mok [2]
;
Hannah L,Williams [11]
;
Jamie R,Kutasovic [5]
;
Margaret C,Cummings [12]
;
Janett,Stoehr [1]
;
Victoria,Lee [1]
;
Kate,Harvey [1]
;
Sunny,Wu [2]
;
Sunil R,Lakhani [5]
;
Peter T,Simpson [5]
;
Thomas R,Cox [2]
;
Lisa M,Ooms [6]
;
Christina A,Mitchell [6]
;
Rob,Salomon [13]
;
Alexander,Swarbrick [2]
;
David,Gallego-Ortega [14]
;
Elgene,Lim [15]
;
Paul,Timpson [2]
;
C Elizabeth,Caldon [16]
作者单位：
Garvan Institute of Medical Research, Sydney, NSW, Australia.
[1]
Garvan Institute of Medical Research, Sydney, NSW, Australia.;School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
[2]
Division of Cell Matrix Biology and Regenerative Medicine, Manchester Cell-Matrix Centre, School of Biological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, UK.
[3]
Westmead Research Hub, Westmead Institute for Medical Research, Westmead, NSW, Australia.
[4]
The University of Queensland, Faculty of Health, Medicine and Behavioural Sciences, Centre for Clinical Research, Brisbane, QLD, Australia.
[5]
Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.
[6]
St George and Sutherland Clinical Campuses, School of Clinical Medicine, UNSW Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.;Department of Anatomical Pathology, NSW Health Pathology, Kogarah, NSW, Australia.
[7]
School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.;ANZUP Cancer Trials Group, Health Translation Hub, Randwick, Sydney, NSW, Australia.;The George Institute for Global Health, Health Translation Hub, Randwick, Sydney, NSW, Australia.
[8]
School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.;Cancer Epigenetic Biology and Therapeutics, Therapeutic Discovery Theme, Children's Cancer Institute, Sydney, NSW, Australia.
[9]
Cancer Epigenetic Biology and Therapeutics, Therapeutic Discovery Theme, Children's Cancer Institute, Sydney, NSW, Australia.
[10]
Garvan Institute of Medical Research, Sydney, NSW, Australia.;Institute for Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.
[11]
The University of Queensland, Faculty of Health, Medicine and Behavioural Sciences, Centre for Clinical Research, Brisbane, QLD, Australia.;Pathology Queensland, The Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.
[12]
Institute for Biomedical Materials and Devices, University of Technology Sydney, Sydney, NSW, Australia.
[13]
Garvan Institute of Medical Research, Sydney, NSW, Australia.;School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.;School of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, NSW, Australia.
[14]
Garvan Institute of Medical Research, Sydney, NSW, Australia.;School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.;St Vincent's Hospital, Darlinghurst, Sydney, NSW, Australia.
[15]
Garvan Institute of Medical Research, Sydney, NSW, Australia. l.caldon@garvan.org.au.;School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia. l.caldon@garvan.org.au.
[16]
医学主题词
人类(Humans);乳腺肿瘤(Breast Neoplasms);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein);女(雌)性(Female);动物(Animals);信号传导(Signal Transduction);小鼠(Mice);细胞系, 肿瘤(Cell Line, Tumor);增量调节(Up-Regulation);鸟嘌呤核苷酸交换因子类(Guanine Nucleotide Exchange Factors);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);抗药性, 肿瘤(Drug Resistance, Neoplasm);他莫昔芬(Tamoxifen);受体, 雌激素(Receptors, Estrogen);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);嘧啶类(Pyrimidines);肿瘤转移(Neoplasm Metastasis);抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);肿瘤复发, 局部(Neoplasm Recurrence, Local);细胞运动(Cell Movement);氨基喹啉类(Aminoquinolines)
DOI
10.1038/s41467-026-70683-x
PMID
42115169
发布时间
2026-05-14
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