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Frequency of mixed neuropathologies in individuals with down syndrome with and without Alzheimer's dementia.

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第一作者: Lisi,Flores-Aguilar
第一单位: Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, 92697, USA.
作者单位: Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, 92697, USA. [1] Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, CA, USA. [2] Institute for Memory Impairments and Neurological Disorders (MIND), University of California Irvine, Irvine, CA, USA. [3] Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, 92697, USA.;Department of Neurology, University of California Irvine, Irvine, CA, USA. [4] Taub Institute for Research On Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.;Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.;Department of Neuroscience, Columbia University, New York, NY, USA. [5] Department of Neurosurgery, University of Colorado Anschutz Medical Center, Aurora, CO, USA. [6] Department of Translational Neuroscience and Neurology, Barrow Neurological Institute, Phoenix, AZ, USA. [7] Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, 92697, USA.;Sue and Bill Gross Stem Cell Center, University of California Irvine, Irvine, CA, USA. [8] Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.;Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.;Geriatric Research Education and Clinical Center, VA Pittsburgh HS, Pittsburgh, PA, USA. [9] Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA. [10] Department of Pediatrics, University of California Irvine, Orange, CA, USA. [11] Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, CA, USA. [12] Department of Neurology, Harvard University, Cambridge, MA, USA. [13] Department of Neurology, Sanders-Brown Center On Aging, University of Kentucky, Lexington, KY, USA. [14] Department of Neurology, Sanders-Brown Center On Aging, University of Kentucky, Lexington, KY, USA.;Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Kentucky, Lexington, KY, USA. [15] Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. [16] Taub Institute for Research On Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.;Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. [17] Department of Neurology, Indiana University, Bloomington, IN, USA. [18] Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, 92697, USA. heade@uci.edu. [19]
DOI 10.1007/s00401-026-03028-z
PMID 42141233
发布时间 2026-06-11
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