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STORM: spatial transcriptomics optimization by resolution via matrix factorization.

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第一作者： Deniz,Gurarslan

第一单位： Institute of Data Science and Artificial Intelligence, Bogazici University, South Campus, Bebek, Besiktas, Istanbul 34342, Turkey.

作者： Deniz,Gurarslan ^[1] ; Oscar,Camargo ^[2] ; Omer,Zeyveli ^[3] ; Yasin,Almalioglu ^[4] ; Yanjun,Li ^[5] ; Mehmet,Turan ^[6] ; Tamer,Kahveci ^[2]

作者单位： Institute of Data Science and Artificial Intelligence, Bogazici University, South Campus, Bebek, Besiktas, Istanbul 34342, Turkey. ^[1] Department of Computer and Information Science and Engineering, University of Florida, 1889 Museum Road, Gainesville, FL 32611, United States. ^[2] Department of Computer Engineering, Fatih Sultan Mehmet Vakif University, Halic Campus, Sutluce, Beyoglu, Istanbul 34445, Turkey. ^[3] Department of Computer Science, University of Oxford, Wolfson Building, Parks Road, Oxford OX1 3QD, United Kingdom. ^[4] Department of Computer and Information Science and Engineering, University of Florida, 1889 Museum Road, Gainesville, FL 32611, United States.;Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development, University of Florida, 1345 Center Drive, Room P3-12, Gainesville, FL 32610, United States. ^[5] Department of Computer Engineering, Bogazici University, Bebek, Besiktas, Istanbul 34342, Turkey. ^[6]

关键词 biologically informed regularization computational pathology gene–gene interaction networks histology-guided modeling multimodal data integration spatial gene–expression reconstruction spatial transcriptomics tensor decomposition tissue heterogeneity tumor microenvironment

医学主题词人类(Humans);算法(Algorithms);基因表达谱(Gene Expression Profiling)

DOI 10.1093/bib/bbag324

PMID 42328842

发布时间 2026-06-22

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