p53 gene inactivation in acute lymphoblastic leukemia of B cell lineage associates with chromosomal breakpoints at 11q23 and 8q24.
第一作者:
C,Lanza
第一单位:
Dipartimento di Scienze Biomediche e Oncologia Umana, Ospedale San Luigi Gonzaga, Torino, Italy.
作者:
医学主题词
碱基序列(Base Sequence);骨髓(Bone Marrow);伯基特淋巴瘤(Burkitt Lymphoma);染色体畸变(Chromosome Aberrations);染色体障碍(Chromosome Disorders);染色体图(Chromosome Mapping);染色体, 人, 11对(Chromosomes, Human, Pair 11);染色体, 人, 8对(Chromosomes, Human, Pair 8);DNA, 肿瘤(DNA, Neoplasm);DNA结合蛋白质类(DNA-Binding Proteins);外显子(Exons);融合蛋白质类, bcr-abl(Fusion Proteins, bcr-abl);基因重排(Gene Rearrangement);基因, myc(Genes, myc);基因, p53(Genes, p53);基因, ras(Genes, ras);组蛋白赖氨酸N-甲基转移酶(Histone-Lysine N-Methyltransferase);人类(Humans);分子序列数据(Molecular Sequence Data);突变(Mutation);髓淋巴细胞性白血病蛋白质(Myeloid-Lymphoid Leukemia Protein);聚合酶链反应(Polymerase Chain Reaction);原癌基因(Proto-Oncogenes);转录因子(Transcription Factors);易位, 遗传(Translocation, Genetic)
PMID
7596184
发布时间
2019-08-16
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