Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide.
作者:
主题词
急性病(Acute Disease);碱基序列(Base Sequence);结合, 竞争性(Binding, Competitive);细胞分化(Cell Differentiation);染色体, 人, 21对(Chromosomes, Human, Pair 21);染色体, 人, 8对(Chromosomes, Human, Pair 8);DNA结合蛋白质类(DNA-Binding Proteins);基因表达(Gene Expression);生长抑制物(Growth Inhibitors);人类(Humans);白血病, 髓样(Leukemia, Myeloid);分子序列数据(Molecular Sequence Data);寡核苷酸类, 反义(Oligonucleotides, Antisense);原癌基因蛋白质类(Proto-Oncogene Proteins);RNA, 信使(RNA, Messenger);重组融合蛋白质类(Recombinant Fusion Proteins);转录因子AP-2(Transcription Factor AP-2);转录因子(Transcription Factors);易位, 遗传(Translocation, Genetic)
DOI
10.1073/pnas.91.24.11723
PMID
7972130
发布时间
2019-05-01
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