Targeted insertions of two exogenous collagen genes into both alleles of their endogenous loci in cultured human cells: the insertions are directed by relatively short fragments containing the promoters and the 5' ends of the genes.
第一作者:
A,Ganguly
第一单位:
Department of Biochemistry and Molecular Biology, Jefferson Institute of Molecular Medicine, Jefferson Medical College, Philadelphia, PA 19107.
作者:
医学主题词
3T3细胞(3T3 Cells);等位基因(Alleles);动物(Animals);染色体, 人, 12对(Chromosomes, Human, Pair 12);克隆, 分子(Cloning, Molecular);胶原(Collagen);黏粒(Cosmids);DNA(DNA);人类(Humans);原位杂交, 荧光(In Situ Hybridization, Fluorescence);小鼠(Mice);分子序列数据(Molecular Sequence Data);启动区, 遗传(Promoter Regions, Genetic);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1073/pnas.91.15.7365
PMID
8041796
发布时间
2019-05-01
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