换一批
换一批Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.
作者：
主题词
动物(Animals);结合部位(Binding Sites);生物转运(Biological Transport);血脑屏障(Blood-Brain Barrier);载体蛋白质类(Carrier Proteins);细胞系(Cell Line);克隆, 分子(Cloning, Molecular);药物设计(Drug Design);GABA拮抗剂(GABA Antagonists);GABA质膜转运蛋白质类(GABA Plasma Membrane Transport Proteins);人类(Humans);配体(Ligands);膜蛋白质类(Membrane Proteins);膜转运蛋白质类(Membrane Transport Proteins);哌啶甲酸类(Nipecotic Acids);有机阴离子转运子(Organic Anion Transporters);脯氨酸(Proline);大鼠(Rats);γ氨基丁酸(gamma-Aminobutyric Acid)
DOI
10.1021/jm00041a012
PMID
8057281
发布时间
2022-03-31
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