Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase.
第一作者:
S,Adachi
第一单位:
Division of Molecular Engineering, Graduate School of Engineering, Kyoto University, Japan.
作者:
医学主题词
苯衍生物(Benzene Derivatives);结合部位(Binding Sites);过氧化氢酶(Catalase);氯化物过氧化物酶(Chloride Peroxidase);半胱氨酸(Cysteine);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);电子自旋共振谱学(Electron Spin Resonance Spectroscopy);血红素(Heme);组氨酸(Histidine);人类(Humans);铁(Iron);磁共振波谱学(Magnetic Resonance Spectroscopy);诱变, 定点(Mutagenesis, Site-Directed);肌红蛋白(Myoglobin);分光光度法(Spectrophotometry);光谱分析, 拉曼(Spectrum Analysis, Raman);酪氨酸(Tyrosine)
DOI
10.1021/bi00052a031
PMID
8380334
发布时间
2019-06-13
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Biochemistry
241-52页
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