换一批High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region.
第一作者：
M J,Churcher
第一单位：
Medical Research Council, Laboratory of Molecular Biology, Cambridge, England.
作者：
医学主题词
氨基酸序列(Amino Acid Sequence);碱基序列(Base Sequence);结合, 竞争性(Binding, Competitive);DNA突变分析(DNA Mutational Analysis);基因表达调控, 病毒(Gene Expression Regulation, Viral);基因产物, tat(Gene Products, tat);HIV长末端重复序列(HIV Long Terminal Repeat);HIV-1(HIV-1);氢键合(Hydrogen Bonding);分子序列数据(Molecular Sequence Data);核酸构象(Nucleic Acid Conformation);肽类(Peptides);蛋白质结合(Protein Binding);RNA, 病毒(RNA, Viral);RNA结合蛋白质类(RNA-Binding Proteins);重组蛋白质类(Recombinant Proteins);构效关系(Structure-Activity Relationship);转录激活(Transcriptional Activation);tat基因产物, 人免疫缺陷病毒(tat Gene Products, Human Immunodeficiency Virus)
DOI
10.1006/jmbi.1993.1128
PMID
8450553
发布时间
2019-07-10
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