Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine.
第一作者:
E T,Baldwin
第一单位:
Frederick Biomedical Supercomputing Center, SAIC-Frederick, NCI-Frederick Cancer Research and Development Center, Maryland 21702, USA.
作者:
主题词
氨基酸序列(Amino Acid Sequence);抗病毒药(Antiviral Agents);结合部位(Binding Sites);结晶学, X线(Crystallography, X-Ray);抗药性, 微生物(Drug Resistance, Microbial);HIV蛋白酶(HIV Protease);HIV蛋白酶抑制药(HIV Protease Inhibitors);氢(Hydrogen);分子序列数据(Molecular Sequence Data);寡肽类(Oligopeptides);丁酸苯酯类(Phenylbutyrates);脯氨酸(Proline);蛋白质构象(Protein Conformation);构效关系(Structure-Activity Relationship);水(Water)
DOI
10.1016/s0969-2126(01)00192-7
PMID
8590019
发布时间
2019-09-14
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Structure (London, England
581-90页
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