The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: inhibition of AP1 binding and activation of a silencer element.
作者:
主题词
碱基序列(Base Sequence);结合部位(Binding Sites);结合, 竞争性(Binding, Competitive);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);DNA(DNA);DNA结合蛋白质类(DNA-Binding Proteins);红系细胞特异性DNA结合因子类(Erythroid-Specific DNA-Binding Factors);基因表达调控(Gene Expression Regulation);人类(Humans);干扰素γ(Interferon-gamma);杀伤细胞, 天然(Killer Cells, Natural);白血病淋巴瘤, 成人T细胞(Leukemia-Lymphoma, Adult T-Cell);模型, 遗传学(Models, Genetic);分子序列数据(Molecular Sequence Data);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);重组融合蛋白质类(Recombinant Fusion Proteins);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);阻遏蛋白质类(Repressor Proteins);转录因子AP-1(Transcription Factor AP-1);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);YY1转录因子(YY1 Transcription Factor)
DOI
10.1128/MCB.16.9.4744
PMID
8756632
发布时间
2021-05-26
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Molecular and cellular biology
4744-53页
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